Depression is associated with impairment of ADL, not motor function in Parkinson disease

被引：57

作者：

Holroyd, S

Currie, LJ

Wooten, GF

机构：

[1] Univ Virginia, Hlth Syst, Dept Psychiat Med, Charlottesville, VA 22908 USA

[2] Univ Virginia, Hlth Syst, Dept Neurol, Charlottesville, VA 22908 USA

来源：

NEUROLOGY | 2005年 / 64卷 / 12期

关键词：

D O I：

10.1212/01.WNL.0000165958.12724.0D

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

Depression was diagnosed in 15% of 100 consecutive patients with Parkinson disease (PD). Depression was associated with lower cognition, history of depression, and a higher Unified Parkinson's Disease Rating Scale score. The latter was due to differences in the activities of daily living (ADL) subscale (17 +/- 7 vs 12 +/- 6; p = 0.004) rather than the motor subscale (30 +/- 13 vs 26 +/- 13; p = 0.27). These results suggest that ADL impairment may in part be due to depression. Patients with PD with poor function should be closely evaluated for depression.

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页码：2134 / 2135

页数：2

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