Suppression of apoptotic DNA fragmentation in herpes simplex virus type 1-infected cells

被引：124

作者：

Koyama, AH ^{[1
]}

Miwa, Y ^{[1
]}

机构：

[1] UNIV TOKUSHIMA,SCH DENT,DEPT BIOCHEM,TOKUSHIMA 770,JAPAN

来源：

JOURNAL OF VIROLOGY | 1997年 / 71卷 / 03期

关键词：

D O I：

10.1128/JVI.71.3.2567-2571.1997

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

HEp-2 cells underwent apoptosis when the cells were incubated in medium containing sorbitol. Infection with herpes simplex virus type 1 (HSV-1) prior to the sorbitol treatment suppressed this apoptosis completely, indicating that HSV-1 carries an antiapoptosis gene. In addition, HSV-1 multiplication was restricted in these apoptotic HEp-2 cells.

引用

页码：2567 / 2571

页数：5

共 27 条

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