Special Issue "Diabetic Nephropathy: Diagnosis, Prevention and Treatment"

被引:269
作者
Ruiz-Ortega, Marta [1 ,2 ]
Rodrigues-Diez, Raul R. [1 ,2 ]
Lavoz, Carolina [3 ]
Rayego-Mateos, Sandra [4 ]
机构
[1] Univ Autonoma Madrid, Mol & Cellular Biol Renal & Vasc Pathol, IIS Fdn Jimenez Diaz, Madrid 28040, Spain
[2] Inst Salud Carlos III, Red Invest Renal REDINREN, Madrid 28029, Spain
[3] Univ Austral Chile, Sch Med, Div Nephrol, Valdivia 5090000, Chile
[4] Inst Recerca Biomed Lleida IRBLleida, Vasc & Renal Translat Res Grp, Lleida 25198, Spain
关键词
chronic kidney disease; diabetic nephropathy; biomarkers; treatment;
D O I
10.3390/jcm9030813
中图分类号
R5 [内科学];
学科分类号
100201 [内科学];
摘要
Diabetic nephropathy (DN) is the main cause of end-stage renal disease. DN is a complex disease mediated by genetic and environmental factors, and many cellular and molecular mechanisms are involved in renal damage in diabetes. There are no biomarkers that reflect the severity of the underlying renal histopathological changes and can effectively predict the progression of renal damage and stratify the risk of DN among individuals with diabetes mellitus. Current therapeutic strategies are based on the strict control of glucose and blood pressure levels and, although there are new anti-diabetic drugs, these treatments only retard renal damage progression, being necessary novel therapies. In this Special Issue, there are several comprehensive reviews and interesting original papers covering all these topics, which would be of interest to the growing number of readers of the Journal of Clinical Medicine.
引用
收藏
页数:4
相关论文
共 11 条
[1]
The Coming Age of Flavonoids in the Treatment of Diabetic Complications [J].
Caro-Ordieres, Teresa ;
Marin-Royo, Gema ;
Opazo-Rios, Lucas ;
Jimenez-Castilla, Luna ;
Antonio Moreno, Juan ;
Gomez-Guerrero, Carmen ;
Egido, Jesus .
JOURNAL OF CLINICAL MEDICINE, 2020, 9 (02)
[2]
Detection and Characterization of a Biochemical Signature Associated with Diabetic Nephropathy Using Near-infrared Spectroscopy on Tissue Sections [J].
De Bruyne, Sander ;
Van Dorpe, Jo ;
Himpe, Jonas ;
Van Biesen, Wim ;
Delanghe, Sigurd ;
Speeckaert, Marijn M. ;
Delanghe, Joris R. .
JOURNAL OF CLINICAL MEDICINE, 2019, 8 (07)
[3]
Therapeutic Potential of Lespedeza bicolor to Prevent Methylglyoxal-Induced Glucotoxicity in Familiar Diabetic Nephropathy [J].
Do, Moon Ho ;
Lee, Jae Hyuk ;
Cho, Kyohee ;
Kang, Min Cheol ;
Subedi, Lalita ;
Parveen, Amna ;
Kim, Sun Yeou .
JOURNAL OF CLINICAL MEDICINE, 2019, 8 (08)
[4]
Inflammatory Targets in Diabetic Nephropathy [J].
Donate-Correa, Javier ;
Luis-Rodriguez, Desiree ;
Martin-Nunez, Ernesto ;
Tagua, Victor G. ;
Hernandez-Carballo, Carolina ;
Ferri, Carla ;
Elena Rodriguez-Rodriguez, Ana ;
Mora-Fernandez, Carmen ;
Navarro-Gonzalez, Juan F. .
JOURNAL OF CLINICAL MEDICINE, 2020, 9 (02)
[5]
Matrix Metalloproteinases in Diabetic Kidney Disease [J].
Garcia-Fernandez, Nuria ;
Jacobs-Cacha, Conxita ;
Maria Mora-Gutierrez, Jose ;
Vergara, Ander ;
Orbe, Josune ;
Jose Soler, Maria .
JOURNAL OF CLINICAL MEDICINE, 2020, 9 (02)
[6]
Urine E-cadherin: A Marker for Early Detection of Kidney Injury in Diabetic Patients [J].
Koziolek, Michael ;
Mueller, Gerhard A. ;
Dihazi, Gry H. ;
Jung, Klaus ;
Altubar, Constanze ;
Wallbach, Manuel ;
Markovic, Ivana ;
Raddatz, Dirk ;
Jahn, Olaf ;
Karakoese, Huelya ;
Lenz, Christof ;
Urlaub, Henning ;
Dihazi, Abdelhi ;
El Meziane, Abdellatif ;
Dihazi, Hassan .
JOURNAL OF CLINICAL MEDICINE, 2020, 9 (03)
[7]
VEGFR2 Blockade Improves Renal Damage in an Experimental Model of Type 2 Diabetic Nephropathy [J].
Lavoz, Carolina ;
Rodrigues-Diez, Raul R. ;
Plaza, Anita ;
Carpio, Daniel ;
Egido, Jesus ;
Ruiz-Ortega, Marta ;
Mezzano, Sergio .
JOURNAL OF CLINICAL MEDICINE, 2020, 9 (02)
[8]
Could IL-17A Be a Novel Therapeutic Target in Diabetic Nephropathy? [J].
Lavoz, Carolina ;
Rayego-Mateos, Sandra ;
Orejudo, Macarena ;
Opazo-Rios, Lucas ;
Marchant, Vanessa ;
Marquez-Exposito, Laura ;
Tejera-Munoz, Antonio ;
Navarro-Gonzalez, Juan F. ;
Droguett, Alejandra ;
Ortiz, Alberto ;
Egido, Jesus ;
Mezzano, Sergio ;
Rodrigues-Diez, Raul R. ;
Ruiz-Ortega, Marta .
JOURNAL OF CLINICAL MEDICINE, 2020, 9 (01)
[9]
Association between Beta2-Adrenergic Receptor Agonists and the Risk of Vascular Complications in Diabetic Patients: A Population-Based Cohort Study [J].
Lee, Hee Jeong ;
Lee, Haekyung ;
Oh, Song Hee ;
Park, Suyeon ;
Jung, Kwang-Young ;
Kim, Hyoungnae ;
Kwon, Soon Hyo ;
Jeon, Jin Seok ;
Han, Dong Cheol ;
Noh, Hyunjin .
JOURNAL OF CLINICAL MEDICINE, 2019, 8 (08)
[10]
The Error of Estimated GFR in Type 2 Diabetes Mellitus [J].
Luis-Lima, Sergio ;
Higueras Linares, Tomas ;
Henriquez-Gomez, Laura ;
Alonso-Pescoso, Raquel ;
Jimenez, Angeles ;
Maria Lopez-Hijazo, Asuncion ;
Negrin-Mena, Natalia ;
Martin, Candelaria ;
Sanchez-Gallego, Macarena ;
Judith Galindo-Hernandez, Sara ;
Fernandez del Castillo, Raquel Socas ;
Castilla-Marrero, Manuel ;
Dominguez-Coello, Santiago ;
Vilchez de Leon, Vanesa ;
Valcarcel-Lopez, Rafael ;
Insausti-Garmendia, Nerea ;
Escamilla, Beatriz ;
Estupinan, Sara ;
Delgado-Mallen, Patricia ;
Armas-Padron, Ana-Maria ;
Marrero-Miranda, Domingo ;
Gonzalez-Rinne, Ana ;
Miquel Rodriguez, Rosa Maria ;
Angeles Cobo-Caso, Maria ;
Diaz-Martin, Laura ;
Gonzalez-Rinne, Federico ;
Gonzalez-Delgado, Alejandra ;
Lopez-Martinez, Marina ;
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Torres, Armando ;
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JOURNAL OF CLINICAL MEDICINE, 2019, 8 (10)