Outdoor air pollution and cystic fibrosis

被引：30

作者：

Brugha, Rossa ^{[1
]}

Edmondson, Claire ^{[1
]}

Davies, Jane C. ^{[1
]}

机构：

[1] Imperial Coll London, Natl Heart & Lung Inst, Gene Therapy, Emmanuel Kaye Bldg,Manresa Rd, London SW3 6LR, England

来源：

PAEDIATRIC RESPIRATORY REVIEWS | 2018年 / 28卷

关键词：

Air pollution; Particulate matter; Exacerbations; Infection; Pseudomonas aeruginosa; LUNG-FUNCTION; PULMONARY EXACERBATIONS; PSEUDOMONAS-AERUGINOSA; OXIDATIVE STRESS; CASE-CROSSOVER; EXPOSURE; CHILDREN; MACROPHAGES; ASSOCIATION; EXPRESSION;

D O I：

10.1016/j.prrv.2018.03.005

中图分类号：

R72 [儿科学];

学科分类号：

100202 [儿科学];

摘要：

Outdoor air pollution is increasingly identified as a contributor to respiratory and cardiovascular disease. Pro-inflammatory particles and gases are inhaled deep into the lungs, and are associated with impaired lung growth and exacerbations of chronic respiratory diseases. The magnitude of these effects are of interest to patients and families, and have been assessed in studies specific to CF. Using systematic review methodology, we sought to collate these studies in order to summarise the known effects of air pollution in cystic fibrosis, and to present information on decreasing personal air pollution exposures. (C) 2018 Elsevier Ltd. All rights reserved.

引用

页码：80 / 86

页数：7

共 53 条

[1]

SERCA2 Regulates Non-CF and CF Airway Epithelial Cell Response to Ozone [J].