Bone marrow and circulating stem/progenitor cells for regenerative cardiovascular therapy

被引:52
作者
Alaiti, Mohamad Amer
Ishikawa, Masakazu
Costa, Marco A. [1 ]
机构
[1] Case Western Reserve Univ, Univ Hosp, Harrington McLaughlin Heart & Vasc Inst, Div Cardiovasc Med, Cleveland, OH 44106 USA
关键词
ENDOTHELIAL PROGENITOR CELLS; ACUTE MYOCARDIAL-INFARCTION; COLONY-STIMULATING FACTOR; CORONARY-ARTERY-DISEASE; LEFT-VENTRICULAR FUNCTION; HEMATOPOIETIC STEM-CELLS; BLOOD MONONUCLEAR-CELLS; CRITICAL LIMB ISCHEMIA; NITRIC-OXIDE SYNTHASE; PERIPHERAL-BLOOD;
D O I
10.1016/j.trsl.2010.06.008
中图分类号
R446 [实验室诊断]; R-33 [实验医学、医学实验];
学科分类号
100118 [医学信息学]; 100208 [临床检验诊断学];
摘要
Cardiovascular disease is the leading cause of death and disability in the Western world. In addition to the advancement of current therapeutic approaches to reduce the associated morbidity and mortality, regenerative medicine and cell-based therapy have been areas of continuous investigation. Circulating and bone-marrow-derived stem or endothelial progenitor cells are an attractive source for regenerative therapy in the cardiovascular field. In this review, we highlight the advantages and limitations of this approach with a focus on key observations from animal studies and clinical trials. (Translational Research 2010;156:112-129)
引用
收藏
页码:112 / 129
页数:18
相关论文
共 173 条
[1]
Adult bone marrow-derived cells for cardiac repair - A systematic review and meta-analysis [J].
Abdel-Latif, Ahmed ;
Bolli, Roberto ;
Tleyjeh, Imad M. ;
Montori, Victor M. ;
Perin, Emerson C. ;
Hornung, Carlton A. ;
Zuba-Surma, Ewa K. ;
Al-Mallah, Mouaz ;
Dawn, Buddhadeb .
ARCHIVES OF INTERNAL MEDICINE, 2007, 167 (10) :989-997
[2]
Increase of circulating endothelial progenitor cells in patients with coronary artery disease after exercise-induced ischemia [J].
Adams, V ;
Lenk, K ;
Linke, A ;
Lenz, D ;
Erbs, S ;
Sandri, M ;
Tarnok, A ;
Gielen, S ;
Emmrich, F ;
Schuler, G ;
Hambrecht, R .
ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY, 2004, 24 (04) :684-690
[3]
Ahmadi H, 2007, CURR NEUROVASC RES, V4, P153
[4]
Essential role of endothelial nitric oxide synthase for mobilization of stem and progenitor cells [J].
Aicher, A ;
Heeschen, C ;
Mildner-Rihm, C ;
Urbich, C ;
Ihling, C ;
Technau-Ihling, K ;
Zeiher, AM ;
Dimmeler, S .
NATURE MEDICINE, 2003, 9 (11) :1370-1376
[5]
Hypoxic preconditioning augments efficacy of human endothelial progenitor cells for therapeutic neovascularization [J].
Akita, T ;
Murohara, T ;
Ikeda, H ;
Sasaki, KI ;
Shimada, T ;
Egami, K ;
Imaizumi, T .
LABORATORY INVESTIGATION, 2003, 83 (01) :65-73
[6]
Autologous Bone Marrow Cell Transplantation Increases Leg Perfusion and Reduces Amputations in Patients With Advanced Critical Limb Ischemia Due to Peripheral Artery Disease [J].
Amann, Berthold ;
Luedemann, Claas ;
Ratei, Richard ;
Schmidt-Lucke, J. Andre .
CELL TRANSPLANTATION, 2009, 18 (03) :371-380
[7]
Isolation of putative progenitor endothelial cells for angiogenesis [J].
Asahara, T ;
Murohara, T ;
Sullivan, A ;
Silver, M ;
vanderZee, R ;
Li, T ;
Witzenbichler, B ;
Schatteman, G ;
Isner, JM .
SCIENCE, 1997, 275 (5302) :964-967
[8]
Bone marrow origin of endothelial progenitor cells responsible for postnatal vasculogenesis in physiological and pathological neovascularization [J].
Asahara, T ;
Masuda, H ;
Takahashi, T ;
Kalka, C ;
Pastore, C ;
Silver, M ;
Kearne, M ;
Magner, M ;
Isner, JM .
CIRCULATION RESEARCH, 1999, 85 (03) :221-228
[9]
HMG-CoA reductase inhibitors reduce senescence and increase proliferation of endothelial progenitor cells via regulation of cell cycle regulatory genes [J].
Assmus, B ;
Urbich, C ;
Aicher, A ;
Hofmann, WK ;
Haendeler, J ;
Rössig, L ;
Spyridopoulos, I ;
Zeiher, AM ;
Dimmeler, S .
CIRCULATION RESEARCH, 2003, 92 (09) :1049-1055
[10]
Transplantation of progenitor cells and regeneration enhancement in acute myocardial infarction -: (TOPCARE-AMI) [J].
Assmus, B ;
Schächinger, V ;
Teupe, C ;
Britten, M ;
Lehmann, R ;
Döbert, N ;
Grünwald, F ;
Aicher, A ;
Urbich, C ;
Martin, H ;
Hoelzer, D ;
Dimmeler, S ;
Zeiher, AM .
CIRCULATION, 2002, 106 (24) :3009-3017