Analysing the composition of outpatient antibiotic use: a tutorial on compositional data analysis

被引：28

作者：

Faes, Christel ^{[1
]}

Molenberghs, Geert ^{[1
,2
]}

Hens, Niel ^{[1
,3
]}

Muller, Arno ^{[4
]}

Goossens, Herman ^{[4
]}

Coenen, Samuel ^{[4
,5
]}

机构：

[1] Univ Hasselt, Interuniv Inst Biostat & Stat Bioinformat I BIOST, Hasselt, Belgium

[2] Catholic Univ Louvain, Interuniv Inst Biostat & Stat Bioinformat I BIOST, B-3000 Louvain, Belgium

[3] Univ Antwerp, CHERMID, Vaccine & Infect Dis Inst VAXINFECTIO, B-2020 Antwerp, Belgium

[4] Univ Antwerp, Lab Med Microbiol, Vaccine & Infect Dis Inst VAXINFECTIO, B-2020 Antwerp, Belgium

[5] Univ Antwerp, Ctr Gen Practice, Vaccine & Infect Dis Inst VAXINFECTIO, B-2020 Antwerp, Belgium

来源：

JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY | 2011年 / 66卷

关键词：

log-ratio analysis; multivariate data; staying-in-the-simplex analysis; ambulatory care; Europe; EUROPEAN SURVEILLANCE;

D O I：

10.1093/jac/dkr461

中图分类号：

R51 [传染病];

学科分类号：

100201 [内科学];

摘要：

In this tutorial, statistical methods for studying outpatient use of antibiotics in Europe are described, using data provided by IMS Health. The methods are applied to two related research questions, namely the assessment of changes in the relative volume of use of different antibiotic subclasses over time and changes in the absolute volume of antibiotic use.

引用

页码：89 / 94

页数：6

共 11 条

[1]

European Surveillance of Antimicrobial Consumption (ESAC): outpatient macrolide, lincosamide and streptogramin (MLS) use in Europe (1997-2009) [J].

Adriaenssens, Niels ;

Coenen, Samuel ;

Versporten, Ann ;

Muller, Arno ;

Minalu, Girma ;

Faes, Christel ;

Vankerckhoven, Vanessa ;

Aerts, Marc ;

Hens, Niel ;

Molenberghs, Geert ;

Goossens, Herman .

JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY, 2011, 66 :37-45

[2]

European Surveillance of Antimicrobial Consumption (ESAC): outpatient quinolone use in Europe (1997-2009) [J].

Adriaenssens, Niels ;

Coenen, Samuel ;

Versporten, Ann ;

Muller, Arno ;

Minalu, Girma ;

Faes, Christel ;

Vankerckhoven, Vanessa ;

Aerts, Marc ;

Hens, Niel ;

Molenberghs, Geert ;

Goossens, Herman .

JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY, 2011, 66 :47-56

[3]

European Surveillance of Antimicrobial Consumption (ESAC): outpatient antibiotic use in Europe (1997-2009) [J].

Adriaenssens, Niels ;

Coenen, Samuel ;

Versporten, Ann ;

Muller, Arno ;

Minalu, Girma ;

Faes, Christel ;

Vankerckhoven, Vanessa ;

Aerts, Marc ;

Hens, Niel ;

Molenberghs, Geert ;

Goossens, Herman .

JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY, 2011, 66 :3-12

[4]

Anderson T.W., 1986, STAT ANAL DATA, V2nd, DOI DOI 10.1007/978-94-009-4109-0

[5]

European Surveillance of Antimicrobial Consumption (ESAC): outpatient use of tetracyclines, sulphonamides and trimethoprim, and other antibacterials in Europe (1997-2009) [J].

Coenen, Samuel ;

Adriaenssens, Niels ;

Versporten, Ann ;

Muller, Arno ;

Minalu, Girma ;

Faes, Christel ;

Vankerckhoven, Vanessa ;

Aerts, Marc ;

Hens, Niel ;

Molenberghs, Geert ;

Goossens, Herman .

JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY, 2011, 66 :57-70

[6]

Application of mixed-effects models to study the country-specific outpatient antibiotic use in Europe: a tutorial on longitudinal data analysis [J].

Minalu, Girma ;

Aerts, Marc ;

Coenen, Samuel ;

Versporten, Ann ;

Muller, Arno ;

Adriaenssens, Niels ;

Beutels, Philippe ;

Molenberghs, Geert ;

Goossens, Herman ;

Hens, Niel .

JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY, 2011, 66 :79-87

[7]

Molenberghs G, 2006, Models for Discrete Longitudinal Data

[8]

Molenberghs Geert., 2000, Linear Mixed Models for Longitudinal Data

[9]

European Surveillance of Antimicrobial Consumption (ESAC): outpatient cephalosporin use in Europe (1997-2009) [J].

Versporten, Ann ;

Coenen, Samuel ;

Adriaenssens, Niels ;

Muller, Arno ;

Minalu, Girma ;

Faes, Christel ;

Vankerckhoven, Vanessa ;

Aerts, Marc ;

Hens, Niel ;

Molenberghs, Geert ;

Goossens, Herman .

JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY, 2011, 66 :25-35

[10]

European Surveillance of Antimicrobial Consumption (ESAC): outpatient penicillin use in Europe (1997-2009) [J].

Versporten, Ann ;

Coenen, Samuel ;

Adriaenssens, Niels ;

Muller, Arno ;

Minalu, Girma ;

Faes, Christel ;

Vankerckhoven, Vanessa ;

Aerts, Marc ;

Hens, Niel ;

Molenberghs, Geert ;

Goossens, Herman .

JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY, 2011, 66 :13-23

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