Interleaflet clear space is reduced in the membrane of COP I and COP II-coated buds/vesicles

被引：14

作者：

Orci, L ^{[1
]}

Schekman, R ^{[1
]}

Perrelet, A ^{[1
]}

机构：

[1] UNIV CALIF BERKELEY,DEPT MOL & CELL BIOL,BERKELEY,CA 94530

来源：

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA | 1996年 / 93卷 / 17期

关键词：

D O I：

10.1073/pnas.93.17.8968

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

Intracellular transfers between membrane-bound compartments occur through vesicles that bud from a donor compartment to fuse subsequently with an acceptor membrane. We report that the membrane that delimits COP I or COP II-coated buds/vesicles from the endoplasmic reticulum and the Golgi complex has a thinner interleaflet clear space as compared with the surrounding, noncoated parental membrane. This change is compatible with a compositional change of the membrane bilayer during the budding process.

引用

页码：8968 / 8970

页数：3

共 20 条

[1] LIPID BILAYERS AND BIOMEMBRANES
BANGHAM, AD
[J]. ANNUAL REVIEW OF BIOCHEMISTRY, 1972, 41 : 753 - +
[2] COPII - A MEMBRANE COAT FORMED BY SEC PROTEINS THAT DRIVE VESICLE BUDDING FROM THE ENDOPLASMIC-RETICULUM
BARLOWE, C
ORCI, L
YEUNG, T
HOSOBUCHI, M
HAMAMOTO, S
SALAMA, N
REXACH, MF
RAVAZZOLA, M
AMHERDT, M
SCHEKMAN, R
[J]. CELL, 1994, 77 (06) : 895 - 907
[3] COPI- and COPII-coated vesicles bud directly from the endoplasmic reticulum in yeast
Bednarek, SY
Ravazzola, M
Hosobuchi, M
Amherdt, M
Perrelet, A
Schekman, R
Orci, L
[J]. CELL, 1995, 83 (07) : 1183 - 1196
[4] CHOLESTEROL AND THE GOLGI-APPARATUS
BRETSCHER, MS
MUNRO, S
[J]. SCIENCE, 1993, 261 (5126) : 1280 - 1281
[5] MAMMALIAN PLASMA-MEMBRANES
BRETSCHER, MS
RAFF, MC
[J]. NATURE, 1975, 258 (5530) : 43 - 49
[6] COATOMER INTERACTION WITH DI-LYSINE ENDOPLASMIC-RETICULUM RETENTION MOTIFS
COSSON, P
LETOURNEUR, F
[J]. SCIENCE, 1994, 263 (5153) : 1629 - 1631
[7] GRIFFITHS G, 1993, FINE STRUCTURE IMMUN, P161
[8] KTISTAKIS NT, 1995, MOL BIOL CELL, V6, P688
[9] COATOMER IS ESSENTIAL FOR RETRIEVAL OF DILYSINE-TAGGED PROTEINS TO THE ENDOPLASMIC-RETICULUM
LETOURNEUR, F
GAYNOR, EC
HENNECKE, S
DEMOLLIERE, C
DUDEN, R
EMR, SD
RIEZMAN, H
COSSON, P
[J]. CELL, 1994, 79 (07) : 1199 - 1207
[10] LISCOVITCH M, 1994, J BIOL CHEM, V269, P21403

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