Titin: Properties and family relationships

被引：264

作者：

Tskhovrebova, L ^{[1
]}

Trinick, J

机构：

[1] Univ Leeds, Astbury Ctr Struct Mol Biol, Leeds LS2 9JT, W Yorkshire, England

[2] Univ Leeds, Sch Biomed Sci, Leeds LS2 9JT, W Yorkshire, England

来源：

NATURE REVIEWS MOLECULAR CELL BIOLOGY | 2003年 / 4卷 / 09期

关键词：

D O I：

10.1038/nrm1198

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

In striated muscles, the rapid production of macroscopic levels of force and displacement stems directly from highly ordered and hierarchical protein organization, with the sarcomere as the elemental contractile unit. There is now a wealth of evidence indicating that the giant elastic protein titin has important roles in controlling the structure and extensibility of vertebrate muscle sarcomeres.

引用

页码：679 / 689

页数：11

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