Neural systems engaged by planning: A PET study of the Tower of London task

被引:470
作者
Baker, SC
Rogers, RD
Owen, AM
Frith, CD
Dolan, RJ
Frackowiak, RSJ
Robbins, TW
机构
[1] INST NEUROL,WELLCOME DEPT COGNIT NEUROL,LONDON WC1N 3BG,ENGLAND
[2] UNIV CAMBRIDGE,DEPT EXPTL PSYCHOL,CAMBRIDGE,ENGLAND
[3] ROYAL FREE HOSP,SCH MED,LONDON,ENGLAND
[4] NATL HOSP NEUROL & NEUROSURG,LONDON WC1N 3BG,ENGLAND
[5] UNIV LONDON UNIV COLL,LONDON WC1E 6BT,ENGLAND
基金
英国惠康基金;
关键词
planning; PET; Tower task; working memory; prefrontal cortex; parietal cortex;
D O I
10.1016/0028-3932(95)00133-6
中图分类号
B84 [心理学]; C [社会科学总论]; Q98 [人类学];
学科分类号
03 ; 0303 ; 030303 ; 04 ; 0402 ;
摘要
The functional anatomy of planning was investigated using the Tower of London task. Activation was observed in a distributed network of cortical areas incorporating prefrontal, cingulate, premotor, parietal and occipital cortices. Activation in corresponding areas has been observed in visuospatial working memory tasks with the exception of the rostral prefrontal cortex. This area may be identified with the executive components of planning comprising response selection and evaluation. Enhanced neural activity in both this rostral prefrontal area and the visuospatial working memory system was associated with increased task difficulty. Copyright (C) 1996 Elsevier Science Ltd.
引用
收藏
页码:515 / 526
页数:12
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