Comment on "Human neuroblasts migrate to the olfactory bulb via a lateral ventricular extension"

被引：85

作者：

Sanai, Nader

Berger, Mitchel S.

Garcia-Verdugo, Jose Manuel

Alvarez-Buylla, Arturo

机构：

[1] Univ Calif San Francisco, Dept Neurol Surg, San Francisco, CA 94143 USA

[2] Univ Valencia, Inst Cavanilles Biodivers & Biol Evolut, Valencia 46071, Spain

[3] Univ Calif San Francisco, Inst Regenerat Med, San Francisco, CA 94143 USA

来源：

SCIENCE | 2007年 / 318卷 / 5849期

关键词：

D O I：

10.1126/science.1145011

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 [理学]; 0710 [生物学]; 09 [农学];

摘要：

Curtis et al. (Research Articles, 2 March 2007, p. 1243) claimed discovery of a human neuronal migratory stream to the olfactory bulb along a putative lateral ventricular extension. However, high levels of proliferation reported with proliferating cell nuclear antigen were not confirmed using different markers, neuronal chain migration was not demonstrated, and no serial reconstruction shows a true ventricular extension.

引用

收藏

页数：2

相关论文

共 15 条

[1]

Evidence of newly generated neurons in the human olfactory bulb [J].

Bédard, A ;

Parent, A .

DEVELOPMENTAL BRAIN RESEARCH, 2004, 151 (1-2) :159-168

[2]

Characterization of the subventricular zone of the adult human brain: evidence for the involvement of Bcl-2 [J].

Bernier, PJ ;

Vinet, J ;

Cossette, M ;

Parent, A .

NEUROSCIENCE RESEARCH, 2000, 37 (01) :67-78

[3]

Increased proliferation reflects glial and vascular-associated changes, but not neurogenesis in the presenile Alzheimer hippocampus [J].

Boekhoorn, Karin ;

Joels, Marian ;

Lucassen, Paul J. .

NEUROBIOLOGY OF DISEASE, 2006, 24 (01) :1-14

[4]

Human neuroblasts migrate to the olfactory bulb via a lateral ventricular extension [J].

Curtis, Maurice A. ;

Kam, Monica ;

Nannmark, Ulf ;

Anderson, Michelle F. ;

Axell, Mathilda Zetterstrom ;

Wikkelso, Carsten ;

Holtas, Stig ;

van Roon-Mom, Willeke M. C. ;

Bjork-Eriksson, Thomas ;

Nordborg, Claes ;

Frisen, Jonas ;

Dragunow, Michael ;

Faull, Richard L. M. ;

Eriksson, Peter S. .

SCIENCE, 2007, 315 (5816) :1243-1249

[5]

The development of the olfactory and the accessory olfactory formations in human embryos and fetuses [J].

Humphrey, T .

JOURNAL OF COMPARATIVE NEUROLOGY, 1940, 73 (03) :431-468

[6]

The generation, migration, and differentiation of olfactory neurons in the adult primate brain [J].

Kornack, DR ;

Rakic, P .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2001, 98 (08) :4752-4757

[7]

Olfactory bulb core is a rich source of neural progenitor and stem cells in adult rodent and human [J].

Liu, ZP ;

Martin, LJ .

JOURNAL OF COMPARATIVE NEUROLOGY, 2003, 459 (04) :368-391

[8]

Chain migration of neuronal precursors [J].

Lois, C ;

GarciaVerdugo, JM ;

AlvarezBuylla, A .

SCIENCE, 1996, 271 (5251) :978-981

[9]

Olfactory bulb volumes in patients with idiopathic Parkinson's disease - a pilot study [J].

Mueller, A ;

Abolmaali, ND ;

Hakimi, AR ;

Gloeckler, T ;

Herting, B ;

Reichmann, H ;

Hummel, T .

JOURNAL OF NEURAL TRANSMISSION, 2005, 112 (10) :1363-1370

[10]

Cellular composition and cytoarchitecture of the adult human subventricular zone:: A niche of neural stem cells [J].

Quinoñes-Hinojosa, A ;

Sanai, N ;

Soriano-Navarro, M ;

Gonzalez-Perez, O ;

Mirzadeh, Z ;

Gil-Perotin, S ;

Romero-Rodriguez, R ;

Berger, MS ;

Garcia-Verdugo, JM ;

Alvarez-Buylla, A .

JOURNAL OF COMPARATIVE NEUROLOGY, 2006, 494 (03) :415-434