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A new family of inhibitors of Mycobacterium tuberculosis thymidine monophosphate kinase
被引:7
作者
:
论文数:
引用数:
h-index:
机构:
Gasse, C.
[
1
]
Huteau, V.
论文数:
0
引用数:
0
h-index:
0
机构:
Inst Pasteur, Dept Biol Struct & Chim, CNRS, URA 2128,Unite Chim Organ, F-75724 Paris 15, France
Inst Pasteur, Dept Biol Struct & Chim, CNRS, URA 2128,Unite Chim Organ, F-75724 Paris 15, France
Huteau, V.
[
1
]
Douguet, D.
论文数:
0
引用数:
0
h-index:
0
机构:
Univ Montpellier 1, INSERM, CNRS, CBS,U5048,U554, Montpellier, France
Inst Pasteur, Dept Biol Struct & Chim, CNRS, URA 2128,Unite Chim Organ, F-75724 Paris 15, France
Douguet, D.
[
2
]
Munier-Lehmann, H.
论文数:
0
引用数:
0
h-index:
0
机构:
Inst Pasteur, Dept Biol Struct & Chim, CNRS, URA 2128,Unite Chim Organ, F-75724 Paris 15, France
Inst Pasteur, Dept Biol Struct & Chim, CNRS, URA 2128,Unite Chim Organ, F-75724 Paris 15, France
Munier-Lehmann, H.
[
1
]
Pochet, S.
论文数:
0
引用数:
0
h-index:
0
机构:
Inst Pasteur, Dept Biol Struct & Chim, CNRS, URA 2128,Unite Chim Organ, F-75724 Paris 15, France
Inst Pasteur, Dept Biol Struct & Chim, CNRS, URA 2128,Unite Chim Organ, F-75724 Paris 15, France
Pochet, S.
[
1
]
机构
:
[1]
Inst Pasteur, Dept Biol Struct & Chim, CNRS, URA 2128,Unite Chim Organ, F-75724 Paris 15, France
[2]
Univ Montpellier 1, INSERM, CNRS, CBS,U5048,U554, Montpellier, France
来源
:
NUCLEOSIDES NUCLEOTIDES & NUCLEIC ACIDS
|
2007年
/ 26卷
/ 8-9期
关键词
:
D O I
:
10.1080/15257770701513349
中图分类号
:
Q5 [生物化学];
Q7 [分子生物学];
学科分类号
:
071010
[生物化学与分子生物学]
;
081704
[应用化学]
;
摘要
:
[No abstract available]
引用
收藏
页码:1057 / 1061
页数:5
相关论文
共 9 条
[1]
X-ray structure of TMP kinase from Mycobacterium tuberculosis complexed with TMP at 1.95 Å resolution
[J].
de la Sierra, IL
论文数:
0
引用数:
0
h-index:
0
机构:
Inst Pasteur, Unite Biochim Struct, F-75724 Paris 15, France
de la Sierra, IL
;
Munier-Lehmann, H
论文数:
0
引用数:
0
h-index:
0
机构:
Inst Pasteur, Unite Biochim Struct, F-75724 Paris 15, France
Munier-Lehmann, H
;
Gilles, AM
论文数:
0
引用数:
0
h-index:
0
机构:
Inst Pasteur, Unite Biochim Struct, F-75724 Paris 15, France
Gilles, AM
;
Bârzu, O
论文数:
0
引用数:
0
h-index:
0
机构:
Inst Pasteur, Unite Biochim Struct, F-75724 Paris 15, France
Bârzu, O
;
Delarue, M
论文数:
0
引用数:
0
h-index:
0
机构:
Inst Pasteur, Unite Biochim Struct, F-75724 Paris 15, France
Delarue, M
.
JOURNAL OF MOLECULAR BIOLOGY,
2001,
311
(01)
:87
-100
[2]
LEA3D: A computer-aided ligand design for structure-based drug design
[J].
Douguet, D
论文数:
0
引用数:
0
h-index:
0
机构:
Univ Montpellier I, Fac Pharm, Ctr Biochim Struct, INSERM UMR U554,CNRS UMR 5048, F-34060 Montpellier, France
Douguet, D
;
Munier-Lehmann, H
论文数:
0
引用数:
0
h-index:
0
机构:
Univ Montpellier I, Fac Pharm, Ctr Biochim Struct, INSERM UMR U554,CNRS UMR 5048, F-34060 Montpellier, France
Munier-Lehmann, H
;
Labesse, G
论文数:
0
引用数:
0
h-index:
0
机构:
Univ Montpellier I, Fac Pharm, Ctr Biochim Struct, INSERM UMR U554,CNRS UMR 5048, F-34060 Montpellier, France
Labesse, G
;
Pochet, S
论文数:
0
引用数:
0
h-index:
0
机构:
Univ Montpellier I, Fac Pharm, Ctr Biochim Struct, INSERM UMR U554,CNRS UMR 5048, F-34060 Montpellier, France
Pochet, S
.
JOURNAL OF MEDICINAL CHEMISTRY,
2005,
48
(07)
:2457
-2468
[3]
Mycobacterium tuberculosis thymidylate kinase:: Structural studies of intermediates along the reaction pathway
[J].
Fioravanti, E
论文数:
0
引用数:
0
h-index:
0
机构:
LCCP, UMR 9015, IBS, F-38027 Grenoble 1, France
Fioravanti, E
;
Haouz, A
论文数:
0
引用数:
0
h-index:
0
机构:
LCCP, UMR 9015, IBS, F-38027 Grenoble 1, France
Haouz, A
;
Ursby, T
论文数:
0
引用数:
0
h-index:
0
机构:
LCCP, UMR 9015, IBS, F-38027 Grenoble 1, France
Ursby, T
;
Munier-Lehmann, H
论文数:
0
引用数:
0
h-index:
0
机构:
LCCP, UMR 9015, IBS, F-38027 Grenoble 1, France
Munier-Lehmann, H
;
Delarue, M
论文数:
0
引用数:
0
h-index:
0
机构:
LCCP, UMR 9015, IBS, F-38027 Grenoble 1, France
Delarue, M
;
Bourgeois, D
论文数:
0
引用数:
0
h-index:
0
机构:
LCCP, UMR 9015, IBS, F-38027 Grenoble 1, France
Bourgeois, D
.
JOURNAL OF MOLECULAR BIOLOGY,
2003,
327
(05)
:1077
-1092
[4]
Thymidylate kinase of Mycobacterium tuberculosis:: A chimera sharing properties common to eukaryotic and bacterial enzymes
[J].
Munier-Lehmann, H
论文数:
0
引用数:
0
h-index:
0
机构:
Inst Pasteur, Lab Chim Struct Macromol, F-75724 Paris 15, France
Munier-Lehmann, H
;
Chaffotte, A
论文数:
0
引用数:
0
h-index:
0
机构:
Inst Pasteur, Lab Chim Struct Macromol, F-75724 Paris 15, France
Chaffotte, A
;
Pochet, S
论文数:
0
引用数:
0
h-index:
0
机构:
Inst Pasteur, Lab Chim Struct Macromol, F-75724 Paris 15, France
Pochet, S
;
Labesse, G
论文数:
0
引用数:
0
h-index:
0
机构:
Inst Pasteur, Lab Chim Struct Macromol, F-75724 Paris 15, France
Labesse, G
.
PROTEIN SCIENCE,
2001,
10
(06)
:1195
-1205
[5]
Comparative study of purine and pyrimidine nucleoside analogues acting on the thymidylate kinases of Mycobacterium tuberculosis and of humans
[J].
Pochet, S
论文数:
0
引用数:
0
h-index:
0
机构:
Inst Pasteur, CNRS, URA 2185, Lab Chim Struct Macromol, F-75724 Paris 15, France
Pochet, S
;
Dugué, L
论文数:
0
引用数:
0
h-index:
0
机构:
Inst Pasteur, CNRS, URA 2185, Lab Chim Struct Macromol, F-75724 Paris 15, France
Dugué, L
;
Labesse, G
论文数:
0
引用数:
0
h-index:
0
机构:
Inst Pasteur, CNRS, URA 2185, Lab Chim Struct Macromol, F-75724 Paris 15, France
Labesse, G
;
Delepierre, M
论文数:
0
引用数:
0
h-index:
0
机构:
Inst Pasteur, CNRS, URA 2185, Lab Chim Struct Macromol, F-75724 Paris 15, France
Delepierre, M
;
Munier-Lehmann, H
论文数:
0
引用数:
0
h-index:
0
机构:
Inst Pasteur, CNRS, URA 2185, Lab Chim Struct Macromol, F-75724 Paris 15, France
Munier-Lehmann, H
.
CHEMBIOCHEM,
2003,
4
(08)
:742
-747
[6]
Pochet S, 2002, CHEMBIOCHEM, V3, P108, DOI 10.1002/1439-7633(20020104)3:1<108::AID-CBIC108>3.0.CO
[7]
2-B
[8]
3′-C-branched-chain-substituted nucleosides and nucleotides as potent inhibitors of Mycobacterium tuberculosis thymidine monophosphate kinase
[J].
Vanheusden, V
论文数:
0
引用数:
0
h-index:
0
机构:
Inst Pasteur, CNRS, Lab Chim Struct Macromol, URA 2128, F-75724 Paris 15, France
Vanheusden, V
;
Munier-Lehmann, H
论文数:
0
引用数:
0
h-index:
0
机构:
Inst Pasteur, CNRS, Lab Chim Struct Macromol, URA 2128, F-75724 Paris 15, France
Munier-Lehmann, H
;
Froeyen, M
论文数:
0
引用数:
0
h-index:
0
机构:
Inst Pasteur, CNRS, Lab Chim Struct Macromol, URA 2128, F-75724 Paris 15, France
Froeyen, M
;
Dugué, L
论文数:
0
引用数:
0
h-index:
0
机构:
Inst Pasteur, CNRS, Lab Chim Struct Macromol, URA 2128, F-75724 Paris 15, France
Dugué, L
;
论文数:
引用数:
h-index:
机构:
Heyerick, A
;
De Keukeleire, D
论文数:
0
引用数:
0
h-index:
0
机构:
Inst Pasteur, CNRS, Lab Chim Struct Macromol, URA 2128, F-75724 Paris 15, France
De Keukeleire, D
;
Pochet, S
论文数:
0
引用数:
0
h-index:
0
机构:
Inst Pasteur, CNRS, Lab Chim Struct Macromol, URA 2128, F-75724 Paris 15, France
Pochet, S
;
Busson, R
论文数:
0
引用数:
0
h-index:
0
机构:
Inst Pasteur, CNRS, Lab Chim Struct Macromol, URA 2128, F-75724 Paris 15, France
Busson, R
;
论文数:
引用数:
h-index:
机构:
Herdewijn, P
;
Van Calenbergh, S
论文数:
0
引用数:
0
h-index:
0
机构:
Inst Pasteur, CNRS, Lab Chim Struct Macromol, URA 2128, F-75724 Paris 15, France
Van Calenbergh, S
.
JOURNAL OF MEDICINAL CHEMISTRY,
2003,
46
(18)
:3811
-3821
[9]
Synthesis and evaluation of thymidine-5′-O-monophosphate analogues as inhibitors of Mycobacterium tuberculosis thymidylate kinase
[J].
Vanheusden, V
论文数:
0
引用数:
0
h-index:
0
机构:
Univ Ghent, Lab Med Chem FFW, B-9000 Ghent, Belgium
Vanheusden, V
;
Munier-Lehmann, H
论文数:
0
引用数:
0
h-index:
0
机构:
Univ Ghent, Lab Med Chem FFW, B-9000 Ghent, Belgium
Munier-Lehmann, H
;
Pochet, S
论文数:
0
引用数:
0
h-index:
0
机构:
Univ Ghent, Lab Med Chem FFW, B-9000 Ghent, Belgium
Pochet, S
;
Herdewijn, P
论文数:
0
引用数:
0
h-index:
0
机构:
Univ Ghent, Lab Med Chem FFW, B-9000 Ghent, Belgium
Herdewijn, P
;
Van Calenbergh, S
论文数:
0
引用数:
0
h-index:
0
机构:
Univ Ghent, Lab Med Chem FFW, B-9000 Ghent, Belgium
Van Calenbergh, S
.
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS,
2002,
12
(19)
:2695
-2698
←
1
→
共 9 条
[1]
X-ray structure of TMP kinase from Mycobacterium tuberculosis complexed with TMP at 1.95 Å resolution
[J].
de la Sierra, IL
论文数:
0
引用数:
0
h-index:
0
机构:
Inst Pasteur, Unite Biochim Struct, F-75724 Paris 15, France
de la Sierra, IL
;
Munier-Lehmann, H
论文数:
0
引用数:
0
h-index:
0
机构:
Inst Pasteur, Unite Biochim Struct, F-75724 Paris 15, France
Munier-Lehmann, H
;
Gilles, AM
论文数:
0
引用数:
0
h-index:
0
机构:
Inst Pasteur, Unite Biochim Struct, F-75724 Paris 15, France
Gilles, AM
;
Bârzu, O
论文数:
0
引用数:
0
h-index:
0
机构:
Inst Pasteur, Unite Biochim Struct, F-75724 Paris 15, France
Bârzu, O
;
Delarue, M
论文数:
0
引用数:
0
h-index:
0
机构:
Inst Pasteur, Unite Biochim Struct, F-75724 Paris 15, France
Delarue, M
.
JOURNAL OF MOLECULAR BIOLOGY,
2001,
311
(01)
:87
-100
[2]
LEA3D: A computer-aided ligand design for structure-based drug design
[J].
Douguet, D
论文数:
0
引用数:
0
h-index:
0
机构:
Univ Montpellier I, Fac Pharm, Ctr Biochim Struct, INSERM UMR U554,CNRS UMR 5048, F-34060 Montpellier, France
Douguet, D
;
Munier-Lehmann, H
论文数:
0
引用数:
0
h-index:
0
机构:
Univ Montpellier I, Fac Pharm, Ctr Biochim Struct, INSERM UMR U554,CNRS UMR 5048, F-34060 Montpellier, France
Munier-Lehmann, H
;
Labesse, G
论文数:
0
引用数:
0
h-index:
0
机构:
Univ Montpellier I, Fac Pharm, Ctr Biochim Struct, INSERM UMR U554,CNRS UMR 5048, F-34060 Montpellier, France
Labesse, G
;
Pochet, S
论文数:
0
引用数:
0
h-index:
0
机构:
Univ Montpellier I, Fac Pharm, Ctr Biochim Struct, INSERM UMR U554,CNRS UMR 5048, F-34060 Montpellier, France
Pochet, S
.
JOURNAL OF MEDICINAL CHEMISTRY,
2005,
48
(07)
:2457
-2468
[3]
Mycobacterium tuberculosis thymidylate kinase:: Structural studies of intermediates along the reaction pathway
[J].
Fioravanti, E
论文数:
0
引用数:
0
h-index:
0
机构:
LCCP, UMR 9015, IBS, F-38027 Grenoble 1, France
Fioravanti, E
;
Haouz, A
论文数:
0
引用数:
0
h-index:
0
机构:
LCCP, UMR 9015, IBS, F-38027 Grenoble 1, France
Haouz, A
;
Ursby, T
论文数:
0
引用数:
0
h-index:
0
机构:
LCCP, UMR 9015, IBS, F-38027 Grenoble 1, France
Ursby, T
;
Munier-Lehmann, H
论文数:
0
引用数:
0
h-index:
0
机构:
LCCP, UMR 9015, IBS, F-38027 Grenoble 1, France
Munier-Lehmann, H
;
Delarue, M
论文数:
0
引用数:
0
h-index:
0
机构:
LCCP, UMR 9015, IBS, F-38027 Grenoble 1, France
Delarue, M
;
Bourgeois, D
论文数:
0
引用数:
0
h-index:
0
机构:
LCCP, UMR 9015, IBS, F-38027 Grenoble 1, France
Bourgeois, D
.
JOURNAL OF MOLECULAR BIOLOGY,
2003,
327
(05)
:1077
-1092
[4]
Thymidylate kinase of Mycobacterium tuberculosis:: A chimera sharing properties common to eukaryotic and bacterial enzymes
[J].
Munier-Lehmann, H
论文数:
0
引用数:
0
h-index:
0
机构:
Inst Pasteur, Lab Chim Struct Macromol, F-75724 Paris 15, France
Munier-Lehmann, H
;
Chaffotte, A
论文数:
0
引用数:
0
h-index:
0
机构:
Inst Pasteur, Lab Chim Struct Macromol, F-75724 Paris 15, France
Chaffotte, A
;
Pochet, S
论文数:
0
引用数:
0
h-index:
0
机构:
Inst Pasteur, Lab Chim Struct Macromol, F-75724 Paris 15, France
Pochet, S
;
Labesse, G
论文数:
0
引用数:
0
h-index:
0
机构:
Inst Pasteur, Lab Chim Struct Macromol, F-75724 Paris 15, France
Labesse, G
.
PROTEIN SCIENCE,
2001,
10
(06)
:1195
-1205
[5]
Comparative study of purine and pyrimidine nucleoside analogues acting on the thymidylate kinases of Mycobacterium tuberculosis and of humans
[J].
Pochet, S
论文数:
0
引用数:
0
h-index:
0
机构:
Inst Pasteur, CNRS, URA 2185, Lab Chim Struct Macromol, F-75724 Paris 15, France
Pochet, S
;
Dugué, L
论文数:
0
引用数:
0
h-index:
0
机构:
Inst Pasteur, CNRS, URA 2185, Lab Chim Struct Macromol, F-75724 Paris 15, France
Dugué, L
;
Labesse, G
论文数:
0
引用数:
0
h-index:
0
机构:
Inst Pasteur, CNRS, URA 2185, Lab Chim Struct Macromol, F-75724 Paris 15, France
Labesse, G
;
Delepierre, M
论文数:
0
引用数:
0
h-index:
0
机构:
Inst Pasteur, CNRS, URA 2185, Lab Chim Struct Macromol, F-75724 Paris 15, France
Delepierre, M
;
Munier-Lehmann, H
论文数:
0
引用数:
0
h-index:
0
机构:
Inst Pasteur, CNRS, URA 2185, Lab Chim Struct Macromol, F-75724 Paris 15, France
Munier-Lehmann, H
.
CHEMBIOCHEM,
2003,
4
(08)
:742
-747
[6]
Pochet S, 2002, CHEMBIOCHEM, V3, P108, DOI 10.1002/1439-7633(20020104)3:1<108::AID-CBIC108>3.0.CO
[7]
2-B
[8]
3′-C-branched-chain-substituted nucleosides and nucleotides as potent inhibitors of Mycobacterium tuberculosis thymidine monophosphate kinase
[J].
Vanheusden, V
论文数:
0
引用数:
0
h-index:
0
机构:
Inst Pasteur, CNRS, Lab Chim Struct Macromol, URA 2128, F-75724 Paris 15, France
Vanheusden, V
;
Munier-Lehmann, H
论文数:
0
引用数:
0
h-index:
0
机构:
Inst Pasteur, CNRS, Lab Chim Struct Macromol, URA 2128, F-75724 Paris 15, France
Munier-Lehmann, H
;
Froeyen, M
论文数:
0
引用数:
0
h-index:
0
机构:
Inst Pasteur, CNRS, Lab Chim Struct Macromol, URA 2128, F-75724 Paris 15, France
Froeyen, M
;
Dugué, L
论文数:
0
引用数:
0
h-index:
0
机构:
Inst Pasteur, CNRS, Lab Chim Struct Macromol, URA 2128, F-75724 Paris 15, France
Dugué, L
;
论文数:
引用数:
h-index:
机构:
Heyerick, A
;
De Keukeleire, D
论文数:
0
引用数:
0
h-index:
0
机构:
Inst Pasteur, CNRS, Lab Chim Struct Macromol, URA 2128, F-75724 Paris 15, France
De Keukeleire, D
;
Pochet, S
论文数:
0
引用数:
0
h-index:
0
机构:
Inst Pasteur, CNRS, Lab Chim Struct Macromol, URA 2128, F-75724 Paris 15, France
Pochet, S
;
Busson, R
论文数:
0
引用数:
0
h-index:
0
机构:
Inst Pasteur, CNRS, Lab Chim Struct Macromol, URA 2128, F-75724 Paris 15, France
Busson, R
;
论文数:
引用数:
h-index:
机构:
Herdewijn, P
;
Van Calenbergh, S
论文数:
0
引用数:
0
h-index:
0
机构:
Inst Pasteur, CNRS, Lab Chim Struct Macromol, URA 2128, F-75724 Paris 15, France
Van Calenbergh, S
.
JOURNAL OF MEDICINAL CHEMISTRY,
2003,
46
(18)
:3811
-3821
[9]
Synthesis and evaluation of thymidine-5′-O-monophosphate analogues as inhibitors of Mycobacterium tuberculosis thymidylate kinase
[J].
Vanheusden, V
论文数:
0
引用数:
0
h-index:
0
机构:
Univ Ghent, Lab Med Chem FFW, B-9000 Ghent, Belgium
Vanheusden, V
;
Munier-Lehmann, H
论文数:
0
引用数:
0
h-index:
0
机构:
Univ Ghent, Lab Med Chem FFW, B-9000 Ghent, Belgium
Munier-Lehmann, H
;
Pochet, S
论文数:
0
引用数:
0
h-index:
0
机构:
Univ Ghent, Lab Med Chem FFW, B-9000 Ghent, Belgium
Pochet, S
;
Herdewijn, P
论文数:
0
引用数:
0
h-index:
0
机构:
Univ Ghent, Lab Med Chem FFW, B-9000 Ghent, Belgium
Herdewijn, P
;
Van Calenbergh, S
论文数:
0
引用数:
0
h-index:
0
机构:
Univ Ghent, Lab Med Chem FFW, B-9000 Ghent, Belgium
Van Calenbergh, S
.
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS,
2002,
12
(19)
:2695
-2698
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