Targeted drug delivery to magnetic implants for therapeutic applications

被引：129

作者：

Yellen, BB

Forbes, ZG

Halverson, DS

Fridman, G

Barbee, KA

Chorny, M

Levy, R

Friedman, G

机构：

[1] Drexel Univ, Dept Elect & Comp Engn, Philadelphia, PA 19104 USA

[2] Drexel Univ, Sch Biomed Engn & Hlth Sci, Philadelphia, PA 19104 USA

[3] Univ Penn, Sch Med, Philadelphia, PA 19104 USA

[4] Childrens Hosp Philadelphia, Philadelphia, PA 19104 USA

来源：

JOURNAL OF MAGNETISM AND MAGNETIC MATERIALS | 2005年 / 293卷 / 01期

关键词：

drug delivery; stent; magnetic implant; local drug delivery; targeted; implant;

D O I：

10.1016/j.jmmm.2005.01.083

中图分类号：

T [工业技术];

学科分类号：

08 ;

摘要：

A new method for locally targeted drug delivery is proposed that employs magnetic implants placed directly in the cardiovascular system to attract injected magnetic carriers. Theoretical simulations and experimental results support the assumption that using magnetic implants in combination with externally applied magnetic field will optimize the delivery of magnetic drug to selected sites within a subject. (c) 2005 Published by Elsevier B.V.

引用

页码：647 / 654

页数：8

共 17 条

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