Paesslerins A and B:: Novel tricyclic sesquiterpenoids from the soft coral Alcyonium paessleri

被引:46
作者
Brasco, MFR [1 ]
Seldes, AM [1 ]
Palermo, JA [1 ]
机构
[1] Univ Buenos Aires, Fac Ciencias Exactas & Nat, Dept Quim Organ, RA-1428 Buenos Aires, DF, Argentina
关键词
D O I
10.1021/ol006684x
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
[GRAPHICS] In the course of our search of new bioactive metabolites from marine invertebrates, paesslerins A and B, sesquiterpenoids with an unprecedented tricyclic skeleton, were isolated from the subAntarctic soft coral Alcyonium paessleri collected at a depth of 200 m near the South Georgia islands, and their structures were elucidated by spectroscopic techniques. These compounds show moderate cytotoxicity in preliminary assays.
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页码:1415 / 1417
页数:3
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