Cellular uptake and saccharide chain elongation of "fluoro-amphiphilic" glycosides

被引：15

作者：

Kasuya, MCZ

Ito, A

Cusi, R

Sato, T

Hatanaka, K

机构：

[1] Univ Tokyo, Inst Ind Sci, Meguro Ku, Tokyo 1538505, Japan

[2] Keio Univ, Grad Sch Sci & Engn, Kouhoku Ku, Yokohama, Kanagawa 2238522, Japan

来源：

CHEMISTRY LETTERS | 2005年 / 34卷 / 06期

关键词：

D O I：

10.1246/cl.2005.856

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Fluoro-amphiphilic glycosides are practical alternatives for the preparation of oligosaccharides. Fluoro-amphiphilic saccharide primers possessing a hydrophilic sugar moiety and a fluorous tag could be taken up by cells and elongated by cellular enzymes. The elongated products were released by cells to the culture medium and could be easily separated from other components by simple extraction with a fluorous solvent.

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收藏

页码：856 / 857

页数：2

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