Mild cognitive impairment and dementia

被引：40

作者：

Albert, Marilyn S. ^{[1
]}

Blacker, Deborah ^{[2
]}

机构：

[1] Johns Hopkins Univ, Sch Med, Dept Neurol, Baltimore, MD 21212 USA

[2] Harvard Univ, Sch Med, Dept Psychiat, Massachusetts Gen Hosp, Boston, MA 02114 USA

来源：

ANNUAL REVIEW OF CLINICAL PSYCHOLOGY | 2006年 / 2卷

关键词：

Alzheimer's disease; MCI; biomarkers; APOE; clinical trials;

D O I：

10.1146/annurev.clinpsy.1.102803.144039

中图分类号：

B849 [应用心理学];

学科分类号：

040203 ;

摘要：

Mild cognitive impairment (MCI) is a clinical syndrome thought to represent the transition between normal function and dementia. This review describes data that support the existence of such a transitional phase, outlines the heterogeneity of MCI and how that has influenced the evolving concept of MCI, and discusses the impact of heterogeneity on recent MCI clinical trials.

引用

页码：379 / 388

页数：10

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