Proteomics in drug discovery

被引：38

作者：

Wang, JH ^{[1
]}

Hewick, RM ^{[1
]}

机构：

[1] Genet Inst, Cambridge, MA 02140 USA

来源：

DRUG DISCOVERY TODAY | 1999年 / 4卷 / 03期

关键词：

D O I：

10.1016/S1359-6446(99)01306-9

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

The promise of genomics has dramatically altered the way drug discovery is now viewed. Overshadowed by the exuberance for genomics are the observations that most disease processes and treatments are manifest at the protein level and that there may not be a good correlation between gene expression and protein expression. An alternative and complementary-approach to genomics is protein expression profiling proteomics. The authors describe the technology, its advantages and some applications.

引用

收藏

页码：129 / 133

页数：5

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