Taste-related activity in the human dorsolateral prefrontal cortex

被引:117
作者
Kringelbach, ML
de Araujo, IET
Rolls, ET
机构
[1] Univ Oxford, Dept Expt Psychol, Oxford OX1 3UD, England
[2] John Radcliffe Hosp, FMRIB, Oxford Ctr Funct Magnet Resonance Imaging, Oxford OX3 9DU, England
基金
英国医学研究理事会;
关键词
taste; dorsolateral; orbitofrontal; insula; fMRI;
D O I
10.1016/j.neuroimage.2003.09.063
中图分类号
Q189 [神经科学];
学科分类号
071006 ;
摘要
Taste remains one of the least-explored human senses. Cortical taste responses were investigated using neuroimaging in 40 subjects tasting a range of different taste stimuli compared to a neutral tasteless control. Activation was found in the anterior insula/frontal opercular taste cortex and caudal orbitofrontal cortex, both areas established as taste cortical areas by neuronal recordings in primates. A novel finding in this study was a highly significant response to taste in the dorsolateral prefrontal cortex. This may reflect an effect of taste on cognitive processing to help optimise or modify behavioural strategies involved in executive control; or it could reflect the engagement of this region in attentional processing by a taste input. (C) 2003 Elsevier Inc. All rights reserved.
引用
收藏
页码:781 / 788
页数:8
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