Radiological evidence of early cerebral microvascular disease in young children with Fabry disease

被引：40

作者：

Cabrera-Salazar, MA

O'Rourke, E

Charria-Ortiz, G

Barranger, JA

机构：

[1] Univ Pittsburgh, Dept Human Genet, Pittsburgh, PA 15261 USA

[2] Univ Miami, Dept Neurol, Miami, FL 33152 USA

来源：

JOURNAL OF PEDIATRICS | 2005年 / 147卷 / 01期

关键词：

D O I：

10.1016/j.jpeds.2005.03.004

中图分类号：

R72 [儿科学];

学科分类号：

100202 [儿科学];

摘要：

We report on 2 children with Fabry disease who had radiologic evidence of microvascular central nervous system involvement despite the clinical absence of renal, cardiac, or cerebral manifestations. This suggests that treatment with enzyme replacement therapy may be necessary early in the disease to avoid irreversible complications.

引用

收藏

页码：102 / 105

页数：4

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