Water-Dispersed Near-Infrared-Emitting Quantum Dots of Ultrasmall Sizes for In Vitro and In Vivo Imaging

被引：128

作者：

He, Yao ^{[1
,2
,3
,4
]}

Zhong, Yiling ^{[1
,2
]}

Su, Yuanyuan ^{[1
,2
,3
,4
]}

Lu, Yimei ^{[1
,2
]}

Jiang, Ziyun ^{[1
,2
]}

Peng, Fei ^{[1
,2
]}

Xu, Tingting ^{[1
,2
,3
,4
]}

Su, Shao ^{[1
,2
,5
]}

Huang, Qing ^{[5
]}

Fan, Chunhai ^{[5
]}

Lee, Shuit-Tong ^{[3
,4
]}

机构：

[1] Soochow Univ, Inst Funct Nano & Soft Mat FUNSOM, Suzhou 215123, Jiangsu, Peoples R China

[2] Soochow Univ, Jiangsu Key Lab Carbon Based Funct Mat & Devices, Suzhou 215123, Jiangsu, Peoples R China

[3] City Univ Hong Kong, Ctr Super Diamond & Adv Films COSDAF, Hong Kong, Hong Kong, Peoples R China

[4] City Univ Hong Kong, Dept Phys & Mat Sci, Hong Kong, Hong Kong, Peoples R China

[5] Chinese Acad Sci, Phys Biol Lab, Shanghai Inst Appl Phys, Shanghai 201800, Peoples R China

来源：

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION | 2011年 / 50卷 / 25期

关键词：

imaging agents; microwave chemistry; quantum dots; tumors; NANOCRYSTALS; DRUG; NANOPARTICLES; NANOSPHERES;

D O I：

10.1002/anie.201004398

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Small but powerful: NIR-emitting CdTe quantum dots (QDs) are directly prepared in aqueous phase through a one-step microwave synthesis. The QDs display excellent aqueous dispersibility, strong luminescence, and high stability. In vitro and in vivo imaging applications show high spectral and spatial resolution. The QDs are efficiently accumulated in tumors of live mice (see picture). Copyright © 2011 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

引用

页码：5694 / 5697

页数：4

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