Genes and structure of selected cytokines involved in pathogenesis of psoriasis

被引：26

作者：

Pietrzak, Aldona ^{[2
]}

Zalewska, Anna ^{[1
]}

Chodorowska, Grazyna ^{[2
]}

Nockowski, Piotr ^{[3
]}

Michalak-Stoma, Anna ^{[4
]}

Osemlak, Pawel ^{[5
]}

Krasowska, Dorota ^{[2
]}

机构：

[1] Med Univ Lodz, Dept Dermatol, PL-94017 Lodz, Poland

[2] Med Univ Lublin, Dept Dermatol, Lublin, Poland

[3] Wroclaw Med Univ, Dept Clin Dermatol Venereol & Allergol, Wroclaw, Poland

[4] Med Univ Lublin, Chair Clin Immunol, Lublin, Poland

[5] Med Univ Lublin, Dept Pediat Surg & Traumatol, Lublin, Poland

来源：

FOLIA HISTOCHEMICA ET CYTOBIOLOGICA | 2008年 / 46卷 / 01期

关键词：

skin disease; psoriasis; interleukins; receptors;

D O I：

10.2478/v10042-008-0002-y

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 [生物化学与分子生物学]; 081704 [应用化学];

摘要：

Psoriasis is a common skin disease involving 1-4% of human population worldwide, of strong genetic background. The following cytokines are directly involved in psoriasis: TNF, IL-1, IL-2, IL-6, IL-7, IL-8, IL-15, IL-18, IL-19, IL-20, IL-23 whereas IL-4, IL-10, IL-12 as well as IL-11, IL-17 and IFN-gamma are rather indirectly engaged. This work is a review of some genetic factors and structure of selected cytokines and receptors and their genes location.

引用

页码：11 / 21

页数：11

共 156 条

[1]

Fine mapping of the psoriasis susceptibility gene PSORS1:: A reassessment of risk associated with a putative risk haplotype lacking HLA-Cw6 [J].

Abecasis, G ;

Allen, M ;

Barker, JNWN ;

Burden, D ;

Capon, F ;

Christophers, E ;

Elder, JT ;

Fischer, J ;

Gudjonsson, JE ;

Hüffmeier, U ;

Jenisch, S ;

Karason, A ;

Kere, J ;

Nair, RP ;

Novelli, G ;

Prud'homme, JF ;

Qin, ZHS ;

Samuelsson, L ;

Sanchez, F ;

Saarialho-Kere, U ;

Ståhle, M ;

Stuart, P ;

Tillman, D ;

Traupe, H ;

Trembath, R ;

Valdimarsson, H ;

Veal, C ;

Voorhees, JJ ;

Weichenthal, M .

JOURNAL OF INVESTIGATIVE DERMATOLOGY, 2005, 124 (05) :921-930

[2]

Aderka Dan, 1996, Cytokine and Growth Factor Reviews, V7, P231, DOI 10.1016/S1359-6101(96)00026-3

[3]

Novel genetic association between the corneodesmosin (MHC S) gene and susceptibility to psoriasis [J].

Ahnini, RT ;

Camp, NJ ;

Cork, MJ ;

Mee, JB ;

Keohane, SG ;

Duff, GW ;

di Giovine, FS .

HUMAN MOLECULAR GENETICS, 1999, 8 (06) :1135-1140

[4]

A non-HLA gene within the MHC in psoriasis [J].

Allen, MH ;

Veal, C ;

Faassen, A ;

Powis, SH ;

Vaughan, RW ;

Trembath, RC ;

Barker, JNWN .

LANCET, 1999, 353 (9164) :1589-1590

[5]

Biological role of interleukin 1 receptor antagonist isoforms [J].

Arend, WP ;

Guthridge, CJ .

ANNALS OF THE RHEUMATIC DISEASES, 2000, 59 :60-64

[6]

Interleukin-10 in cutaneous disorders:: implications for its pathophysiological importance and therapeutic use [J].

Asadullah, K ;

Sabat, R ;

Wiese, A ;

Döcke, WD ;

Volk, HD ;

Sterry, W .

ARCHIVES OF DERMATOLOGICAL RESEARCH, 1999, 291 (12) :628-636

[7]

Asadullah Khusru, 2004, Current Drug Targets - Inflammation and Allergy, V3, P185, DOI 10.2174/1568010043343886

[8]

Psoriasis susceptibility locus on 18p revealed by genome scan in Finnish families not associated with PSORS1 [J].

Asumalahti, K ;

Laitinen, T ;

Lahermo, P ;

Suomela, S ;

Itkonen-Vatjus, R ;

Jansen, C ;

Karvonen, J ;

Karvonen, SL ;

Reunala, T ;

Snellman, E ;

Uurasmaa, T ;

Saarialho-Kere, U ;

Kere, J .

JOURNAL OF INVESTIGATIVE DERMATOLOGY, 2003, 121 (04) :735-740

[9]

BARNA M, 1994, ACTA DERM-VENEREOL, V74, P9

[10]

Barrie AM, 2005, CLIN APPL IMMUNOL RE, V5, P225

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