Dementia with Lewy bodies and AD are not associated with occipital lobe atrophy on MRI

被引：69

作者：

Middelkoop, HAM

van der Flier, WM

Burton, EJ

Lloyd, AJ

Paling, S

Barber, R

Ballard, C

McKeith, IG

O'Brien, JT

机构：

[1] Univ Newcastle Upon Tyne, Inst Ageing & Hlth, Newcastle Upon Tyne NE1 7RU, Tyne & Wear, England

[2] Leiden Univ, Med Ctr, Dept Neurol, Leiden, Netherlands

[3] Leiden Univ, Med Ctr, Dept Expt & Theoret Psychol, Leiden, Netherlands

来源：

NEUROLOGY | 2001年 / 57卷 / 11期

关键词：

D O I：

10.1212/WNL.57.11.2117

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

Dementia with Lewy bodies (DLB) is associated with occipital changes in blood flow and metabolism, but structural changes in this region have not previously been assessed. The authors performed volumetric MRI measurement of the occipital lobe blind to the diagnosis in 23 subjects with DLB, 25 with AD, and 24 age-matched control subjects. There were no significant differences between groups in occipital lobe volume. The authors conclude gross structural changes in the occipital lobe do not occur in patients with mild to moderate DLB or AD.

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页码：2117 / 2120

页数：4

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