Familial focal segmental glomerulosclerosis

被引：30

作者：

Kaplan, J

Pollak, MR

机构：

[1] Brigham & Womens Hosp, Dept Med, Div Renal, Boston, MA 02115 USA

[2] Harvard Univ, Sch Med, Boston, MA USA

来源：

CURRENT OPINION IN NEPHROLOGY AND HYPERTENSION | 2001年 / 10卷 / 02期

关键词：

D O I：

10.1097/00041552-200103000-00005

中图分类号：

R5 [内科学]; R69 [泌尿科学（泌尿生殖系疾病）];

学科分类号：

1002 ; 100201 ;

摘要：

There is increasing recognition of the importance of genetic factors in the development of focal segmental glomerulosclerosis and related proteinuric disorders. Recently, four genes have been identified which, when defective, cause focal segmental glomerulosclerosis or nephrosis, All of these genes appear to be important in the maintenance of glomerular podocyte function. However, not all cases of familial nephrosis or proteinuria are explained by defects in these genes. Curr Opin Nephrol Hypertens 10:183-187. (C) 2001 Lippincott Williams & Wilkins.

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收藏

页码：183 / 187

页数：5

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