Cowpox with severe generalized eruption, Finland

被引：89

作者：

Pelkonen, PM

Tarvainen, K

Hynninen, A

Kallio, ERK

Henttonen, H

Palva, A

Vaheri, A

Vapalahti, O

机构：

[1] Univ Helsinki, Dept Virol, Haartman Inst, FIN-00014 Helsinki, Finland

[2] Fac Med Vet, Helsinki, Finland

[3] Cent Hosp N Karelia, Joensuu, Finland

[4] Finnish Forest Res Inst, Vantaa, Finland

[5] HUCH Lab Diagnost, Helsinki, Finland

来源：

EMERGING INFECTIOUS DISEASES | 2003年 / 9卷 / 11期

关键词：

D O I：

10.3201/eid0911.020814

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

Cowpox with a severe, generalized eruption was diagnosed in an atopic 4-year-old girl by electron microscopy, virus isolation, polymerase chain reaction, and immunoglobulin (Ig) M and low-avidity IgG antibodies. The hemagglutinin gene of the isolate clustered with a Russian cowpox virus strain, and more distantly, with other cowpox and vaccinia virus strains. The patient's dog had orthopoxvirus-specific antibodies, indicating a possible transmission route. In Finnish wild rodents, orthopoxvirus seroprevalences were 0%-92%, in humans the seroprevalence was 100% in the age group > 50, decreasing towards younger age groups.

引用

页码：1458 / 1461

页数：4

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