Successful treatment of extramammary Paget's disease of the scrotum with imiquimod 5% cream

被引：42

作者：

Berman, B ^{[1
]}

Spencer, J

Villa, A

Poochareon, V

Elgart, G

机构：

[1] Univ Miami, Miami, FL 33152 USA

[2] Mt Sinai Med Ctr, New York, NY 10029 USA

来源：

CLINICAL AND EXPERIMENTAL DERMATOLOGY | 2003年 / 28卷

关键词：

D O I：

10.1046/j.1365-2230.28.s1.12.x

中图分类号：

R75 [皮肤病学与性病学];

学科分类号：

100206 ;

摘要：

Extramammary Paget's disease (EMPD) of the skin is an uncommon malignancy involving the epidermis, which sometimes extends into the dermis. Current treatments for EMPD are surgical excision, Mobs' micrographic surgery or laser ablation. We report a case of a 68-year-old male who presented with recurrent EMPD. The patient refused to have surgery and, as an alternative, he applied imiquimod 5% cream, an immune response modifier, daily for a total of 6 weeks. During the initial weeks of therapy, he experienced moderate erythema. Imiquimod treatment resulted in clinical and histological eradication of EMPD, with no recurrence observed during 6 months of follow-up.

引用

页码：36 / 38

页数：3

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