Effects of the presence of sulfonamides in the environment and their influence on human health

被引：581

作者：

Baran, Wojciech ^{[1
]}

Adamek, Ewa ^{[1
]}

Ziemianska, Justyna ^{[2
]}

Sobczak, Andrzej ^{[1
,2
]}

机构：

[1] Silesian Med Univ, Dept Gen & Analyt Chem, PL-41200 Sosnowiec, Poland

[2] Inst Occupat Med & Environm Hlth, PL-41200 Sosnowiec, Poland

来源：

JOURNAL OF HAZARDOUS MATERIALS | 2011年 / 196卷

关键词：

Sulfonamides; Biotransformation; Ecotoxicity; Environmental risk; Drug resistance; WASTE-WATER TREATMENT; SOLID-PHASE EXTRACTION; TANDEM MASS-SPECTROMETRY; SEWAGE-TREATMENT PLANTS; SOIL MICROBIAL ACTIVITY; ESCHERICHIA-COLI; ANTIMICROBIAL RESISTANCE; VETERINARY ANTIBIOTICS; PHOTOCATALYTIC DEGRADATION; SURFACE WATERS;

D O I：

10.1016/j.jhazmat.2011.08.082

中图分类号：

X [环境科学、安全科学];

学科分类号：

08 ; 0830 ;

摘要：

World production and consumption of pharmaceuticals has been steadily increasing. Anti-infectives have been particularly important in modern therapy of microbial infection. Sulfonamides have been widely used for a long time as anti-infectives and are still widely prescribed today. This review presents the most common types of sulfonamides used in healthcare and veterinary medicine and discusses the problems connected with their presence in the biosphere. Based on the analysis of over 160 papers, it was found that small amounts of sulfonamides present in the environment were mainly derived from agricultural activities. These drugs have caused changes in the population of microbes that could be potentially hazardous to human health. This human health hazard could have a global range, and administrative activities have been ineffective in risk reduction. (C) 2011 Elsevier B.V. All rights reserved.

引用

页码：1 / 15

页数：15

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