Eukaryotic DNA replication origins: Reconciling disparate data

被引:23
作者
DePamphilis, ML [1 ]
机构
[1] NICHHD, NIH, Bethesda, MD 20892 USA
关键词
D O I
10.1016/S0092-8674(03)00604-4
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
In this issue of Cell, Anglana and coworkers provide new insight into the nature of mammalian replication origins that helps to reconcile the divergent views that emerged over the past decade. Taken together with other studies, we can see how replication origins have evolved in response to the demands of animal development.
引用
收藏
页码:274 / 275
页数:2
相关论文
共 10 条
[1]   Dynamics of DNA replication in mammalian somatic cells: Nucleotide pool modulates origin choice and interorigin spacing [J].
Anglana, M ;
Apiou, F ;
Bensimon, A ;
Debatisse, M .
CELL, 2003, 114 (03) :385-394
[2]   Role for a Drosophila Myb-containing protein complex in site-specific DNA replication [J].
Beall, EL ;
Manak, JR ;
Zhou, S ;
Bell, M ;
Lipsick, JS ;
Botchan, MR .
NATURE, 2002, 420 (6917) :833-837
[3]   DNA replication in eukaryotic cells [J].
Bell, SP ;
Dutta, A .
ANNUAL REVIEW OF BIOCHEMISTRY, 2002, 71 :333-374
[4]  
DePamphilis ML, 1999, BIOESSAYS, V21, P5, DOI 10.1002/(SICI)1521-1878(199901)21:1<5::AID-BIES2>3.0.CO
[5]  
2-6
[6]   MAPPING REPLICATION UNITS IN ANIMAL-CELLS [J].
HANDELI, S ;
KLAR, A ;
MEUTH, M ;
CEDAR, H .
CELL, 1989, 57 (06) :909-920
[7]   Site-specific ORC binding, pre-replication complex assembly and DNA synthesis at Schizosaccharomyces pombe replication origins [J].
Kong, DC ;
DePamphilis, ML .
EMBO JOURNAL, 2002, 21 (20) :5567-5576
[8]   Replication of the chicken β-globin locus:: Early-firing origins at the 5′ HS4 insulator and the ρ- and βA-globin genes show opposite epigenetic modifications [J].
Prioleau, MN ;
Gendron, MC ;
Hyrien, O .
MOLECULAR AND CELLULAR BIOLOGY, 2003, 23 (10) :3536-3549
[9]   Multiple ORC-binding sites are required for efficient MCM loading and origin firing in fission yeast [J].
Takahashi, T ;
Ohara, E ;
Nishitani, H ;
Masukata, H .
EMBO JOURNAL, 2003, 22 (04) :964-974
[10]   REPLICATION INITIATES IN A BROAD ZONE IN THE AMPLIFIED CHO DIHYDROFOLATE-REDUCTASE DOMAIN [J].
VAUGHN, JP ;
DIJKWEL, PA ;
HAMLIN, JL .
CELL, 1990, 61 (06) :1075-1087