Optofluidic trapping and transport on solid core waveguides within a microfluidic device

被引:215
作者
Schmidt, Bradley S. [1 ]
Yang, Allen H. J.
Erickson, David
Lipson, Michal
机构
[1] Cornell Univ, Sch Elect & Comp Engn, Ithaca, NY 14853 USA
[2] Cornell Univ, Sch Chem & Biomol Engn, Ithaca, NY 14853 USA
[3] Cornell Univ, Sibley Sch Mech & Aerosp Engn, Ithaca, NY 14853 USA
来源
OPTICS EXPRESS | 2007年 / 15卷 / 22期
关键词
D O I
10.1364/OE.15.014322
中图分类号
O43 [光学];
学科分类号
070207 ; 0803 ;
摘要
In this work we demonstrate an integrated microfluidic/photonic architecture for performing dynamic optofluidic trapping and transport of particles in the evanescent field of solid core waveguides. Our architecture consists of SU-8 polymer waveguides combined with soft lithography defined poly(dimethylsiloxane) (PDMS) microfluidic channels. The forces exerted by the evanescent field result in both the attraction of particles to the waveguide surface and propulsion in the direction of optical propagation both perpendicular and opposite to the direction of pressure-driven flow. Velocities as high as 28 mu m/s were achieved for 3 mu m diameter polystyrene spheres with an estimated 53.5 mW of guided optical power at the trapping location. The particle-size dependence of the optical forces in such devices is also characterized. (C) 2007 Optical Society of America.
引用
收藏
页码:14322 / 14334
页数:13
相关论文
共 34 条
[1]   Radiation forces on a micrometer-sized sphere in an evanescent field [J].
Almaas, E ;
Brevik, I .
JOURNAL OF THE OPTICAL SOCIETY OF AMERICA B-OPTICAL PHYSICS, 1995, 12 (12) :2429-2438
[2]   Optical trapping, manipulation, and sorting of cells and colloids in microfluidic systems with diode laser bars [J].
Applegate, RW ;
Squier, J ;
Vestad, T ;
Oakey, J ;
Marr, DWM .
OPTICS EXPRESS, 2004, 12 (19) :4390-4398
[3]  
Arai F, 2001, ELECTROPHORESIS, V22, P283, DOI 10.1002/1522-2683(200101)22:2<283::AID-ELPS283>3.0.CO
[4]  
2-C
[5]   OBSERVATION OF A SINGLE-BEAM GRADIENT FORCE OPTICAL TRAP FOR DIELECTRIC PARTICLES [J].
ASHKIN, A ;
DZIEDZIC, JM ;
BJORKHOLM, JE ;
CHU, S .
OPTICS LETTERS, 1986, 11 (05) :288-290
[6]   Single-mode TE00-TM00 optical waveguides on SU-8 polymer [J].
Bêche, B ;
Pelletier, N ;
Gaviot, E ;
Zyss, J .
OPTICS COMMUNICATIONS, 2004, 230 (1-3) :91-94
[7]  
Brenner H., 1965, Low Reynolds number hydrodynamics: with special applications to Particulate Media
[8]   Integrated monolithic optical manipulation [J].
Cran-McGreehin, Simon ;
Krauss, Thomas F. ;
Dholakia, Kishan .
LAB ON A CHIP, 2006, 6 (09) :1122-1124
[9]   Rapid prototyping of microfluidic systems in poly(dimethylsiloxane) [J].
Duffy, DC ;
McDonald, JC ;
Schueller, OJA ;
Whitesides, GM .
ANALYTICAL CHEMISTRY, 1998, 70 (23) :4974-4984
[10]   Optical tweezers applied to a microfluidic system [J].
Enger, J ;
Goksör, M ;
Ramser, K ;
Hagberg, P ;
Hanstorp, D .
LAB ON A CHIP, 2004, 4 (03) :196-200