Glycans and neural cell interactions

被引:422
作者
Kleene, R [1 ]
Schachner, M [1 ]
机构
[1] Univ Hamburg, Zentrum Mol Neurobiol, D-20246 Hamburg, Germany
关键词
D O I
10.1038/nrn1349
中图分类号
Q189 [神经科学];
学科分类号
071006 ;
摘要
Carbohydrate-carrying molecules in the nervous system have important roles during development, regeneration and synaptic plasticity. Carbohydrates mediate interactions between recognition molecules, thereby contributing to the formation of a complex molecular meshwork at the cell surface and in the extracellular matrix. The tremendous structural diversity of glycan chains allows for immense combinatorial possibilities that might underlie the fine-tuning of cell-cell and cell-matrix interactions.
引用
收藏
页码:195 / 208
页数:14
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