A mild and convenient 'dry' hydrolysis of amides to carboxylic acids

被引：11

作者：

Chemat, F ^{[1
]}

机构：

[1] Univ Reunion, Fac Sci & Technol, Lab Chim Subst Nat & Sci Aliments, F-97715 St Denis 9, France

来源：

TETRAHEDRON LETTERS | 2000年 / 41卷 / 20期

关键词：

hydrolysis; amides; carboxylic acids and derivatives;

D O I：

10.1016/S0040-4039(00)00507-4

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A one-pot preparation of carboxylic acids is described that proceeds from their corresponding amides by a 'dry' hydrolysis with phthalic anhydride in the absence of water and solvent. The method affords carboxylic acids in good yields and is applicable to a variety of substrates. (C) 2000 Elsevier Science Ltd. All rights reserved.

引用

页码：3855 / 3857

页数：3

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