Mps1 checks up on chromosome attachment

被引:2
作者
Hauf, Silke [1 ]
机构
[1] Max Planck Gesell, Friedrich Miescher Lab, D-72076 Tubingen, Germany
关键词
D O I
10.1016/j.cell.2008.01.008
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
The protein kinase Mps1, a crucial regulator of the spindle-assembly checkpoint, now turns out to be essential for correcting errors in chromosome attachment (Jelluma et al., 2008). Mps1 exerts this effect by regulating the activity of the Aurora B kinase through phosphorylation of its partner protein Borealin.
引用
收藏
页码:181 / 182
页数:3
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