Chronic urticaria: What is new, where are we headed

被引：11

作者：

Ferrer, M. ^{[1
]}

Kaplan, A. P. ^{[2
]}

机构：

[1] Univ Navarra, Clin Univ, Dept Allergy, E-31080 Pamplona, Spain

[2] Urticaria Ctr Charleston, Charleston, SC USA

来源：

ALLERGOLOGIA ET IMMUNOPATHOLOGIA | 2007年 / 35卷 / 02期

关键词：

chronic urticaria; cutaneous inflammation; angioedema; interleukins; lymphocytes Th1-Th2; mast cells; basophils;

D O I：

10.1157/13101339

中图分类号：

R392 [医学免疫学];

学科分类号：

100102 ;

摘要：

Chronic urticaria can be defined as the occurrence of widespread daily or nearly daily wheals for at least 6 weeks, which may be accompanied by angioedema. It is a disease with a considerable impact on patients' quality of life. Furthermore, these patients may undergo extensive laboratory evaluations seeking a cause only to be frustrated when none is found. There is no curative treatment for this disorder and we do not understand the mechanisms that lead to the onset of disease. However, in recent years there have been significant advances in the understanding of some of the molecular mechanisms that cause cutaneous inflammation that is manifest as urticaria and angioedema. In this review we will summarize our recent contributions to this field and try to offer insights regarding future directions for research.

引用

页码：57 / 61

页数：5

共 43 条

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