Facile strategy to well-defined water-soluble boronic acid (co)polymers

被引：137

作者：

Cambre, Jennifer N. ^{[1
]}

Roy, Debashish ^{[1
]}

Gondi, Sudershan R. ^{[1
]}

Sumerlin, Brent S. ^{[1
]}

机构：

[1] So Methodist Univ, Dept Chem, Dallas, TX 75275 USA

来源：

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY | 2007年 / 129卷 / 34期

关键词：

D O I：

10.1021/ja074239s

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

A facile route to well-defined boronic acid (co)polymers from stable and easily manipulated boronic ester monomers is presented. The polymerization of 4-pinacolatoborylstyrene by reversible addition-fragmentation chain transfer (RAFT) yielded polymeric boronic acid precursors. Selection of stoichiometry allowed tuning of polymerization kinetics and targeting specific molecular weights in the range of M-n = 17000-32000 g/mol. The resulting low polydispersity poly(4-pinacolatoborylstyrene) homopolymers were employed as macro-chain transfer agents for block copolymerization with N,N-dimethylacrylamide to yield amphiphilic block copolymers that formed micelles in aqueous media. The pinacol ester derivatized (co)polymers were easily deprotected by a mild and convenient strategy to yield free boronic acid polymers.

引用

页码：10348 / +

页数：3

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