Synthesis of cyclic sulfamoyl carbamates and ureas via ring-closing metathesis

被引：18

作者：

Dougherty, JM

Jiménez, M

Hanson, PR

机构：

[1] Univ Kansas, Dept Chem, Lawrence, KS 66045 USA

[2] Univ Kansas, KU Chem Methodol & Lib Dev Ctr Excellence, Lawrence, KS 66047 USA

来源：

TETRAHEDRON | 2005年 / 61卷 / 26期

基金：

美国国家卫生研究院;

关键词：

cyclic sulfamoyl carbamate; cyclic sulfamoyl urea; sulfur heterocycles; RCM; metathesis;

D O I：

10.1016/j.tet.2005.03.140

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Synthetic routes to a diverse set of cyclic sulfamoyl carbamates and ureas are reported. These routes utilize 3-component coupling, Mitsunobu alkylation, and ring-closing metathesis using the second-generation Grubbs catalyst to achieve the synthesis of the target S-heterocyclic compounds. Cyclic S-heterocycles ranging from 9- to 11-membered rings have been obtained. (c) 2005 Elsevier Ltd. All rights reserved.

引用

收藏

页码：6218 / 6230

页数：13

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