Myelinated nerves: Filling in the juxtaparanodal gap

被引：6

作者：

Brophy, PJ ^{[1
]}

机构：

[1] Univ Edinburgh, Neurosci Res Ctr, Edinburgh EH9 1RJ, Midlothian, Scotland

来源：

CURRENT BIOLOGY | 2003年 / 13卷 / 24期

关键词：

D O I：

10.1016/j.cub.2003.11.041

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The nodes of Ranvier of myelinated nerves are flanked by paranodal axoglial junctions and these are bounded by juxtaparanodal domains. New constituents of the juxtaparanode have been identified recently, though their function remains enigmatic.

引用

页码：R956 / R957

页数：2

共 18 条

[1] Axon-glia interactions and the domain organization of myelinated axons requires Neurexin IV/Caspr/Paranodin [J].

Bhat, MA ;

Rios, JC ;

Lu, Y ;

Garcia-Fresco, GP ;

Ching, W ;

St Martin, M ;

Li, JJ ;

Einheber, S ;

Chesler, M ;

Rosenbluth, J ;

Salzer, JL ;

Bellen, HJ .

NEURON, 2001, 30 (02) :369-383

[2] Contactin orchestrates assembly of the septate-like junctions at the paranode in myelinated peripheral nerve [J].

Boyle, MET ;

Berglund, EO ;

Murai, KK ;

Weber, L ;

Peles, E ;

Ranscht, B .

NEURON, 2001, 30 (02) :385-397

[3] Axoglial junctions: Separate the channels or scramble the message [J].

Brophy, PJ .

CURRENT BIOLOGY, 2001, 11 (14) :R555-R557

[4] Neurofascin is a glial receptor for the paranodin/Caspr-contactin axonal complex at the axoglial junction [J].

Charles, P ;

Tait, S ;

Faivre-Sarrailh, C ;

Barbin, G ;

Gunn-Moore, F ;

Denisenko-Nehrbass, N ;

Guennoc, AM ;

Girault, JA ;

Brophy, PJ ;

Lubetzki, C .

CURRENT BIOLOGY, 2002, 12 (03) :217-220

[5] Analysis of potassium channel functions in mammalian axons by gene knockouts [J].

Chiu, SY ;

Zhou, L ;

Zhang, CL ;

Messing, A .

JOURNAL OF NEUROCYTOLOGY, 1999, 28 (4-5) :349-364

[6]

CHIU SY, 1979, J PHYSIOL-LONDON, V292, P149, DOI 10.1113/jphysiol.1979.sp012843

[7] Errors in corticospinal axon guidance in mice lacking the neural cell adhesion molecule L1 [J].

Cohen, NR ;

Taylor, JSH ;

Scott, LB ;

Guillery, RW ;

Soriano, P ;

Furley, AJW .

CURRENT BIOLOGY, 1998, 8 (01) :26-33

[8] Protein 4.1B associates with both Caspr/paranodin and Caspr2 at paranodes and juxtaparanodes of myelinated fibres [J].

Denisenko-Nehrbass, N ;

Oguievetskaia, K ;

Goutebroze, L ;

Galvez, T ;

Yamakawa, H ;

Ohara, O ;

Carnaud, M ;

Girault, JA .

EUROPEAN JOURNAL OF NEUROSCIENCE, 2003, 17 (02) :411-416

[9]

Devaux J, 2003, J NEUROSCI, V23, P4509

[10] The axonal membrane protein Caspr, a homologue of neurexin IV, is a component of the septate-like paranodal junctions that assemble during myelination [J].

Einheber, S ;

Zanazzi, G ;

Ching, W ;

Scherer, S ;

Milner, TA ;

Peles, E ;

Salzer, JL .

JOURNAL OF CELL BIOLOGY, 1997, 139 (06) :1495-1506

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