Correlation of exhaled nitric oxide, spirometry and asthma symptoms

被引：83

作者：

Spergel, JM

Fogg, MI

Bokszczanin-Knosala, A

机构：

[1] Childrens Hosp Philadelphia, Allergy Sect, Div Allergy & Immunol, Philadelphia, PA 19104 USA

[2] Univ Penn, Sch Med, Div Pulm Allergy & Crit Care, Philadelphia, PA 19104 USA

来源：

JOURNAL OF ASTHMA | 2005年 / 42卷 / 10期

关键词：

asthma; exhaled nitric oxide; symptom score; spirometry;

D O I：

10.1080/02770900500371344

中图分类号：

R392 [医学免疫学];

学科分类号：

100102 [免疫学];

摘要：

Asthma is the most common chronic disease of childhood. Asthma severity is monitored by spirometry. However, this does not directly measure airway inflammation. Exhaled nitric oxide (FeNO) is a proposed method to measure airway inflammation non-invasively. Previous studies have shown that FeNO correlates with endobronchial biopsies and symptoms in patients with asthma. We monitored daily asthma symptoms compared to monthly spirometry and FeNO. Total monthly symptom scores correlated with both forced expiratory volume at 1 sec (FEV1) and FeNO. FeNO had a strong correlation than FEV1 . FeNO and FEV1 were not correlated. We propose that FeNO should be used as an additional monitoring tool for asthma.

引用

页码：879 / 883

页数：5

共 29 条

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