Waldenstrom's macroglobulinemia associated with AA amyloidosis

被引:21
作者
Gardyn, J
Schwartz, A
Gal, R
Lewinski, U
Kristt, D
Cohen, AM
机构
[1] Rabin Med Ctr, Hematol Unit, IL-49372 Petah Tiqwa, Israel
[2] Rabin Med Ctr, Inst Pathol, IL-49372 Petah Tiqwa, Israel
[3] Tel Aviv Univ, Sackler Sch Med, IL-69978 Tel Aviv, Israel
关键词
secondary amyloidosis; Waldenstrom's macroglobulinemia; nephrotic syndrome;
D O I
10.1007/BF02982553
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
It is widely accepted that amyloidosis in Waldenstrom's macroglobulinemia (WM) is exclusively due to amyloid light-chain deposition. However, only a small number of previous reports have actually characterized the type of amyloid in WM. We now report the third patient with WM and amyloid A protein (AA) amyloidosis. This patient developed malabsorption, nephrotic syndrome, and orthostatic hypotension. AA was immunohistochemically demonstrated in the rectal biopsy. In conjunction with previous examples of AA amyloidosis, the present report raises the possibility that AA amyloidosis may also occur in WM patients. (C) 2001 The Japanese Society of Hematology.
引用
收藏
页码:76 / 78
页数:3
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