An enantioconvergent route to (-)-kainic acid

被引：36

作者：

Nakada, Y ^{[1
]}

Sugahara, T ^{[1
]}

Ogasawara, K ^{[1
]}

机构：

[1] TOHOKU UNIV,INST PHARMACEUT,SENDAI,MIYAGI 98077,JAPAN

来源：

TETRAHEDRON LETTERS | 1997年 / 38卷 / 05期

关键词：

D O I：

10.1016/S0040-4039(96)02467-7

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A new stereocontrolled route to (-)-kainic acid, the representative of the kainoid amino acids and exhibiting insecticidal, anthelmintic and neuroexcitatory properties, has been devised in an enantioconvergent way using either (+)- or (-)-ketodicyclopentadiene as the starting material by employing a concurrent retro-Diels-Alder reaction and intramolecular ene reaction as the key step. (C) 1997, Elsevier Science Ltd.

引用

页码：857 / 860

页数：4

共 17 条

[1]

DOWLE MD, 1979, CHEM SOC REV, P171

[2] SYNTHESES OF KAINOIDS [J].