Aluminum in enteral nutrition formulas and parenteral solutions

被引:12
作者
Baydar, T
Aydin, A
Duru, S
Isimer, A
Sahin, G
机构
[1] HACETTEPE UNIV, FAC PHARM, DEPT TOXICOL, TR-06100 ANKARA, TURKEY
[2] GULHANE MIL MED ACAD, ANKARA, TURKEY
来源
JOURNAL OF TOXICOLOGY-CLINICAL TOXICOLOGY | 1997年 / 35卷 / 03期
关键词
D O I
10.3109/15563659709001212
中图分类号
R99 [毒物学(毒理学)];
学科分类号
100405 [卫生毒理学];
摘要
Background: To examine the aluminum content of several commercially available enteral nutrition formulas and parenteral solutions. Methods: Twelve enteral nutrition formulas and 10 parenteral solutions were commonly used in routine clinical care of patients and obtained from different medical companies in Turkey, The aluminum contents were determined by electrothermal atomic absorption spectrophotometry. Results: We found that aluminum concentration in the enteral nutrition formulas and the parenteral solutions to range from 87.6 to 961.2 ng/mL and 58.4 to 1232.0 ng/mL, respectively. Conclusions: Careful clinical and biochemical monitoring are warranted to determine whether it will be necessary to eliminate aluminum contamination of enteral and parenteral preparations used in patients, particularly infants, with reduced kidney function who may be at risk for aluminum intoxication.
引用
收藏
页码:277 / 281
页数:5
相关论文
共 18 条
[1]
ALUMINUM [J].
ALFREY, AC .
ADVANCES IN CLINICAL CHEMISTRY, 1983, 23 :69-91
[2]
[Anonymous], 1986, PEDIATRICS, V78, P1150
[3]
Baydar T, 1996, TRACE ELEM ELECTROLY, V13, P50
[4]
BOUGLE D, 1991, TRACE ELEM MED, V8, P172
[5]
CHADWICK DJ, 1992, ALUMINUM BIOL MED, P1
[6]
METABOLISM AND POSSIBLE HEALTH-EFFECTS OF ALUMINUM [J].
GANROT, PO .
ENVIRONMENTAL HEALTH PERSPECTIVES, 1986, 65 :363-441
[7]
Gruskin A B, 1988, Adv Pediatr, V35, P281
[8]
HEPATIC ALUMINUM ACCUMULATION IN CHILDREN ON TOTAL PARENTERAL-NUTRITION [J].
KLEIN, GL ;
BERQUIST, WE ;
AMENT, ME ;
COBURN, JW ;
MILLER, NL ;
ALFREY, AC .
JOURNAL OF PEDIATRIC GASTROENTEROLOGY AND NUTRITION, 1984, 3 (05) :740-743
[9]
PARENTERAL DRUG PRODUCTS CONTAINING ALUMINUM AS AN INGREDIENT OR A CONTAMINANT - RESPONSE TO FDA NOTICE OF INTENT [J].
KLEIN, GL .
AMERICAN JOURNAL OF CLINICAL NUTRITION, 1991, 53 (02) :399-402
[10]
KLEIN GL, 1991, NUTR REV, V49, P74, DOI 10.1111/j.1753-4887.1991.tb07409.x