Highly conserved protein kinases involved in the regulation of carbon and amino acid metabolism

被引：53

作者：

Halford, NG ^{[1
]}

Hey, S ^{[1
]}

Jhurreea, D ^{[1
]}

Laurie, S ^{[1
]}

McKibbin, RS ^{[1
]}

Zhang, YH ^{[1
]}

Paul, MJ ^{[1
]}

机构：

[1] Rothamsted Res, Crop Performance & Improvement, Harpenden AL5 2JQ, Herts, England

来源：

JOURNAL OF EXPERIMENTAL BOTANY | 2004年 / 55卷 / 394期

基金：

英国生物技术与生命科学研究理事会;

关键词：

amino acid metabolism; carbon metabolism; plant protein kinases; regulation; signalling;

D O I：

10.1093/jxb/erh019

中图分类号：

Q94 [植物学];

学科分类号：

071001 ;

摘要：

It has been clear for over a decade and a half that ancient signalling pathways controlling fundamental cellular processes are highly conserved throughout the eukaryotes. Two plant protein kinases, sucrose non-fermenting 1 (SNF1)-related protein kinase (SnRK1) and general control non-derepressible 2 (GCN2)-related protein kinase are reviewed here. These protein kinases show an extraordinary level of conservation with their fungal and animal homologues given the span of time since they diverged from them. However, close examination of the signalling pathways in which they operate also reveals intriguing differences in activation and function.

引用

页码：35 / 42

页数：8

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