Manganous phosphate acts as a superoxide dismutase

被引：150

作者：

Barnese, Kevin ^{[2
]}

Gralla, Edith B. ^{[2
]}

Cabelli, Diane E. ^{[1
]}

Valentine, Joan Selverstone ^{[2
]}

机构：

[1] Brookhaven Natl Lab, Dept Chem, Upton, NY 11573 USA

[2] Univ Calif Los Angeles, Dept Chem & Biochem, Los Angeles, CA 90095 USA

来源：

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY | 2008年 / 130卷 / 14期

关键词：

D O I：

10.1021/ja710162n

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

A substantial body of evidence indicates that high intracellular concentrations of inorganic manganous ions render some cells resistant to ionizing radiation and provide substantial antioxidant protection to aerobic cells lacking superoxide dismutase (SOD) enzymes. We found that manganous salts studied in its ability to remove superoxide rapidly and catalytically from aqueous solution via a disproportionation mechanism that is entirely different from those of the SOD enzymes.

引用

页码：4604 / +

页数：4

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