The future of functional MRI in clinical medicine

被引：51

作者：

Bullmore, Edward T. ^{[1
,2
]}

机构：

[1] Univ Cambridge, Behav & Clin Neurosci Inst, Dept Psychiat, Cambridge CB2 0SZ, England

[2] GlaxoSmithKline, Cambridge, England

来源：

NEUROIMAGE | 2012年 / 62卷 / 02期

关键词：

Psychiatry; Neurology; Therapeutics; Translational; Genetic; Drug; DORSOLATERAL PREFRONTAL CORTEX; GENERIC BRAIN ACTIVATION; PHYSIOLOGICAL DYSFUNCTION; WORKING-MEMORY; CONNECTIVITY; SCHIZOPHRENIA; METAANALYSIS; FMRI; HYPOFRONTALITY; DEPRESSION;

D O I：

10.1016/j.neuroimage.2012.01.026

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

In the last 20 years or so, functional MRI has matured very rapidly from being an experimental imaging method in the hands of a few labs to being a very widely available and widely used workhorse of cognitive neuroscience and clinical neuroscience research internationally. FMRI studies have had a considerable impact on our understanding of brain system phenotypes of neurological and psychiatric disorders; and some impact already on development of new therapeutics. However, the direct benefit of fMRI to individual patients with brain disorders has so far been minimal. Here I provide a personal perspective on what has already been achieved, and imagine how the further development of fMRI over the medium term might lead to even greater engagement with clinical medicine. (C) 2012 Elsevier Inc. All rights reserved.

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页码：1267 / 1271

页数：5

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