Neonatal halothane anesthesia affects cortical morphology

被引：7

作者：

Nuñez, JL

Juraska, JM

机构：

[1] Univ Illinois, Neurosci Program, Champaign, IL 61820 USA

[2] Univ Illinois, Dept Psychol, Champaign, IL 61820 USA

来源：

DEVELOPMENTAL BRAIN RESEARCH | 2000年 / 124卷 / 1-2期

关键词：

development; rat; surgery;

D O I：

10.1016/S0165-3806(00)00093-6

中图分类号：

Q [生物科学];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

Neonatal cryoanesthesia has recently been documented to affect morphology and behavior after a single exposure [Dev. Brain Res. 111 (1998) 89; Horm. Behav. 37 (2000) 169]. In the current experiment. we investigated the effect of one-time exposure to halothane inhalant anesthesia on neonatal rats of both sexes. Fifteen minutes of exposure on postnatal day one resulted in detectable changes in the volume of the visual cortex at 3 months. Thus, neonatal halothane alters neural development and its effects are observable in the adult rat. (C) 2000 Elsevier Science B.V. All rights reserved.

引用

页码：121 / 124

页数：4

共 14 条

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[2]

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