Sarcopenia and Fragility Fractures: Molecular and Clinical Evidence of the Bone-Muscle Interaction

被引：117

作者：

Tarantino, Umberto

Piccirilli, Eleonora

Fantini, Massimo

Baldi, Jacopo

Gasbarra, Elena

Bei, Roberto

机构：

[1] Univ Hosp Fdn, Dept Orthopaed & Traumatol, Rome, Italy

[2] Univ Roma Tor Vergata, Dept Clin Sci & Translat Med, Rome, Italy

来源：

JOURNAL OF BONE AND JOINT SURGERY-AMERICAN VOLUME | 2015年 / 97A卷 / 05期

关键词：

MINERAL DENSITY; OSTEOPOROTIC FRACTURES; POSTMENOPAUSAL WOMEN; NUTRITIONAL-STATUS; GROWTH-HORMONE; OLDER-ADULTS; PREVALENCE; MEN; AGE; EPIDEMIOLOGY;

D O I：

10.2106/JBJS.N.00648

中图分类号：

R826.8 [整形外科学]; R782.2 [口腔颌面部整形外科学]; R726.2 [小儿整形外科学]; R62 [整形外科学（修复外科学）];

学科分类号：

100224 [整形外科学];

摘要：

Bone and muscle tissues are in close relationship, and the aging process is a factor involved in the loss of the functionality of both bones and muscles. Sarcopenia and osteoporosis are linked from a biological and functional perspective and are related to an increased fracture risk in the elderly. The increased fracture risk in sarcopenic and osteoporotic subjects is due to the decline of muscle mass and strength, the decrease in bone mineral density, and limited mobility. © 2015 By The Journal of Bone and Joint Surgery, Incorporated.

引用

页码：429 / 437

页数：9

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