Improvement and decline in tactile discrimination behavior after cortical plasticity induced by passive tactile coactivation

被引：89

作者：

Hodzic, A

Veit, R

Karim, AA

Erb, M

Godde, B

机构：

[1] Univ Tubingen, Inst Med Psychol & Behav Neurobiol, D-72074 Tubingen, Germany

[2] Grad Sch Neural & Behav Sci, Int Max Planck Res Sch, D-72074 Tubingen, Germany

[3] Dept Neuroradiol, Sect Expt Magnet Resonance Cent Nervous Syst, D-72076 Tubingen, Germany

[4] Univ Hosp, Dept Neurol, D-72076 Tubingen, Germany

来源：

JOURNAL OF NEUROSCIENCE | 2004年 / 24卷 / 02期

关键词：

functional MRI; psychophysics; perceptual learning; input statistics; somatosensory cortex; human;

D O I：

10.1523/JNEUROSCI.3731-03.2004

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

Perceptual learning can be induced by passive tactile coactivation without attention or reinforcement. We used functional MRI (fMRI) and psychophysics to investigate in detail the specificity of this type of learning for different tactile discrimination tasks and the underlying cortical reorganization. We found that a few hours of Hebbian coactivation evoked a significant increase of primary (SI) and secondary (SII) somatosensory cortical areas representing the stimulated body parts. The amount of plastic changes was strongly correlated with improvement in spatial discrimination performance. However, in the same subjects, frequency discrimination was impaired after coactivation, indicating that even maladaptive processes can be induced by intense passive sensory stimulation.

引用

页码：442 / 446

页数：5

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