Role of calcineurin in striated muscle: development, adaptation, and disease

被引：55

作者：

Bassel-Duby, R ^{[1
]}

Olson, EN ^{[1
]}

机构：

[1] Univ Texas, SW Med Ctr, Dept Biol Mol, Dallas, TX 75390 USA

来源：

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS | 2003年 / 311卷 / 04期

基金：

美国国家卫生研究院;

关键词：

D O I：

10.1016/j.bbrc.2003.09.020

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Striated muscles, cardiac and skeletal muscles, use calcium as a second messenger to respond and adapt to environmental stimuli. Elevations in intracellular calcium activate calcineurin, a serine/threonine phosphatase, resulting in expression of a set of genes involved in remodeling striated muscle. Activation of calcineurin in hearts produces cardiac hypertrophy, and in skeletal muscle promotes cell differentiation and transforms fiber type specificity. In this review we discuss the effects of calcineurin activity on development, adaptation, and disease of striated muscle. (C) 2003 Elsevier Inc. All rights reserved.

引用

页码：1133 / 1141

页数：9

共 94 条

[1] Activation and cellular localization of the cyclosporine A-sensitive transcription factor NF-AT in skeletal muscle cells
Abbott, KL
Friday, BB
Thaloor, D
Murphy, TJ
Pavlath, GK
[J]. MOLECULAR BIOLOGY OF THE CELL, 1998, 9 (10) : 2905 - 2916
[2] Intracellular calcium and myosin isoform transitions - Calcineurin and calcium-calmodulin kinase pathways regulate preferential activation of the iia myosin heavy chain promoter
Allen, DL
Leinwand, LA
[J]. JOURNAL OF BIOLOGICAL CHEMISTRY, 2002, 277 (47) : 45323 - 45330
[3] Different pathways regulate expression of the skeletal myosin heavy chain genes
Allen, DL
Sartorius, CA
Sycuro, LK
Leinwand, LA
[J]. JOURNAL OF BIOLOGICAL CHEMISTRY, 2001, 276 (47) : 43524 - 43533
[4] Aramburu J, 2000, CURR TOP CELL REGUL, V36, P237
[5] Calcineurin regulates ryanodine receptor/Ca2+-release channels in rat heart
Bandyopadhyay, A
Shin, DW
Ahn, JO
Kim, DH
[J]. BIOCHEMICAL JOURNAL, 2000, 352 : 61 - 70
[6] Calcium ion in skeletal muscle:: Its crucial role for muscle function, plasticity, and disease
Berchtold, MW
Brinkmeier, H
Müntener, M
[J]. PHYSIOLOGICAL REVIEWS, 2000, 80 (03) : 1215 - 1265
[7] The versatility and universality of calcium signalling
Berridge, MJ
Lipp, P
Bootman, MD
[J]. NATURE REVIEWS MOLECULAR CELL BIOLOGY, 2000, 1 (01) : 11 - 21
[8] Calcineurin co-regulates contractile and metabolic components of slow muscle phenotype
Bigard, X
Sanchez, H
Zoll, J
Mateo, P
Rousseau, V
Veksler, V
Ventura-Clapier, R
[J]. JOURNAL OF BIOLOGICAL CHEMISTRY, 2000, 275 (26) : 19653 - 19660
[9] Cellular adaptations of skeletal muscles to cyclosporine
Biring, MS
Fournier, M
Ross, DJ
Lewis, MI
[J]. JOURNAL OF APPLIED PHYSIOLOGY, 1998, 84 (06) : 1967 - 1975
[10] Akt/mTOR pathway is a crucial regulator of skeletal muscle hypertrophy and can prevent muscle atrophy in vivo
Bodine, SC
Stitt, TN
Gonzalez, M
Kline, WO
Stover, GL
Bauerlein, R
Zlotchenko, E
Scrimgeour, A
Lawrence, JC
Glass, DJ
Yancopoulos, GD
[J]. NATURE CELL BIOLOGY, 2001, 3 (11) : 1014 - 1019

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