Coupling calcium to SNARE-mediated synaptic vesicle fusion

被引：28

作者：

Hilfiker, S

Greengard, P

Augustine, GJ

机构：

[1] Rockefeller Univ, New York, NY 10021 USA

[2] Duke Univ, Med Ctr, Dept Neurobiol, Durham, NC 27710 USA

来源：

NATURE NEUROSCIENCE | 1999年 / 2卷 / 02期

关键词：

D O I：

10.1038/5659

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

Calcium triggers vesicle fusion, but the molecular mechanism is largely unknown. Now Ilardi and colleagues identify Snapin, a protein that may provide the missing link.

引用

页码：104 / 106

页数：3

共 15 条

[1] Exocytosis: Proteins and perturbations [J].

Augustine, GJ ;

Burns, ME ;

DeBello, WM ;

Pettit, DL ;

Schweizer, FE .

ANNUAL REVIEW OF PHARMACOLOGY AND TOXICOLOGY, 1996, 36 :659-701

[2]

AUGUSTINE GJ, 1991, ANN NY ACAD SCI, V635, P363

[3] INHIBITION OF NEUROTRANSMITTER RELEASE BY C2-DOMAIN PEPTIDES IMPLICATES SYNAPTOTAGMIN IN EXOCYTOSIS [J].

BOMMERT, K ;

CHARLTON, MP ;

DEBELLO, WM ;

CHIN, GJ ;

BETZ, H ;

AUGUSTINE, GJ .

NATURE, 1993, 363 (6425) :163-165

[4] ABSENCE OF SYNAPTOTAGMIN DISRUPTS EXCITATION-SECRETION COUPLING DURING SYNAPTIC TRANSMISSION [J].

BROADIE, K ;

BELLEN, HJ ;

DIANTONIO, A ;

LITTLETON, JT ;

SCHWARZ, TL .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1994, 91 (22) :10727-10731

[5] PROTEIN-PROTEIN INTERACTIONS CONTRIBUTING TO THE SPECIFICITY OF INTRACELLULAR VESICULAR TRAFFICKING [J].

CALAKOS, N ;

BENNETT, MK ;

PETERSON, KE ;

SCHELLER, RH .

SCIENCE, 1994, 263 (5150) :1146-1149

[6] SYNAPTOTAGMIN-I - A MAJOR CA2+ SENSOR FOR TRANSMITTER RELEASE AT A CENTRAL SYNAPSE [J].

GEPPERT, M ;

GODA, Y ;

HAMMER, RE ;

LI, C ;

ROSAHL, TW ;

STEVENS, CF ;

SUDHOF, TC .

CELL, 1994, 79 (04) :717-727

[7]

Kee Y, 1996, J NEUROSCI, V16, P1975

[8] CA2+-DEPENDENT AND CA2+-INDEPENDENT ACTIVITIES OF NEURAL AND NONNEURAL SYNAPTOTAGMINS [J].

LI, C ;

ULLRICH, B ;

ZHANG, JZ ;

ANDERSON, RGW ;

BROSE, N ;

SUDHOF, TC .

NATURE, 1995, 375 (6532) :594-599

[9] RELATIONSHIP BETWEEN PRESYNAPTIC CALCIUM CURRENT AND POSTSYNAPTIC POTENTIAL IN SQUID GIANT SYNAPSE [J].

LLINAS, R ;

STEINBERG, IZ ;

WALTON, K .

BIOPHYSICAL JOURNAL, 1981, 33 (03) :323-351

[10] SNAP-25 and synaptotagmin involvement in the final Ca2+-dependent triggering of neurotransmitter exocytosis [J].

Mehta, PP ;

Battenberg, E ;

Wilson, MC .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1996, 93 (19) :10471-10476

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