Effects of enoxaparin on late pregnancy complications and neonatal outcome in women with recurrent pregnancy loss and thrombophilia: results from the Live-Enox study

被引:41
作者
Brenner, B
Bar, J
Ellis, M
Yarom, I
Yohai, D
Samueloff, A
机构
[1] Rambam Med Ctr, Thrombosis & Hemostasis Unit, IL-31096 Haifa, Israel
[2] Rabin Med Ctr, Petah Tiqwa, Israel
[3] Meir Med Ctr Blood Bank, Kefar Sava, Israel
[4] Haemek Med Ctr, Afula, Israel
[5] Soroka Med Ctr, IL-84101 Beer Sheva, Israel
[6] Shaare Zedek Med Ctr, Jerusalem, Israel
关键词
D O I
10.1016/j.fertnstert.2005.03.048
中图分类号
R71 [妇产科学];
学科分类号
100211 ;
摘要
Women with thrombophilia and a history of recurrent pregnancy loss have poor pregnancy outcomes. Prophylaxis with enoxaparin 40 mg/day or 80 mg/day resulted in favorable gestational and neonatal outcomes.
引用
收藏
页码:770 / 773
页数:4
相关论文
共 13 条
[1]  
Brenner B, 2000, THROMB HAEMOSTASIS, V83, P693
[2]   Efficacy and safety of two doses of enoxaparin in women with thrombophilia and recurrent pregnancy loss: the LIVE-ENOX study [J].
Brenner, B ;
Hoffman, R ;
Carp, H ;
Dulitsky, M ;
Younis, J .
JOURNAL OF THROMBOSIS AND HAEMOSTASIS, 2005, 3 (02) :227-229
[3]   Clinical management of thrombophilia-related placental vascular complications [J].
Brenner, B .
BLOOD, 2004, 103 (11) :4003-4009
[4]   Inherited thrombophilia and pregnancy loss [J].
Brenner, B .
BEST PRACTICE & RESEARCH CLINICAL HAEMATOLOGY, 2003, 16 (02) :311-320
[5]   Thromboprophylaxis improves the live birth rate in women with consecutive recurrent miscarriages and hereditary thrombophilia [J].
Carp, H ;
Dolitzky, M ;
Inbal, A .
JOURNAL OF THROMBOSIS AND HAEMOSTASIS, 2003, 1 (03) :433-438
[6]   The use of low-molecular-weight heparin for the management of venous thromboembolism in pregnancy [J].
Eldor, A .
EUROPEAN JOURNAL OF OBSTETRICS & GYNECOLOGY AND REPRODUCTIVE BIOLOGY, 2002, 104 (01) :3-13
[7]   Low-molecular-weight heparin versus low-dose aspirin in women with one fetal logs and a constitutional thrombophilic disorder [J].
Gris, JC ;
Mercier, E ;
Quéré, I ;
Lavigne-Lissalde, G ;
Cochery-Nouvellon, E ;
Hoffet, M ;
Ripart-Neveu, S ;
Tailland, ML ;
Dauzat, M ;
Marès, P .
BLOOD, 2004, 103 (10) :3695-3699
[8]  
GRIS JC, 1995, THROMB HAEMOSTASIS, V73, P362
[9]  
Gris JC, 2002, THROMB HAEMOSTASIS, V87, P536
[10]   Increased frequency of genetic thrombophilia in women with complications of pregnancy [J].
Kupferminc, MJ ;
Eldor, A ;
Steinman, N ;
Many, A ;
Bar-Am, A ;
Jaffa, A ;
Fait, G ;
Lessing, JB .
NEW ENGLAND JOURNAL OF MEDICINE, 1999, 340 (01) :9-13