Cell traffic and the lymphatic endothelium

被引:73
作者
Johnson, Louise A. [1 ]
Jackson, David G. [1 ]
机构
[1] John Radcliffe Hosp, MRC, Human Immunol Unit, Weatherall Inst Mol Med, Oxford OX3 9DS, England
来源
LYMPHATIC CONTINUUM REVISITED | 2008年 / 1131卷
基金
英国医学研究理事会;
关键词
ICAM-1; VCAM-1; dendritic cell; CCL21; CCR7; transmigration; inflammation; LYVE-1;
D O I
10.1196/annals.1413.011
中图分类号
O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];
学科分类号
07 [理学]; 0710 [生物学]; 09 [农学];
摘要
The principal immune function of the afferent lymphatics is to bear antigen and leukocytes from peripheral tissues to the draining lymph nodes. Recent research has shown that passage of leukocytes into the afferent lymphatic capillaries is far from an indolent process; rather it is carefully orchestrated by an array of adhesion molecules, as well as by chemokines and their receptors. Here we review the current knowledge of leukocyte trans-lymphatic endothelial migration and its role in the development of an immune response.
引用
收藏
页码:119 / 133
页数:15
相关论文
共 106 条
[1]
Neutrophils rapidly migrate via lymphatics after Mycobacterium bovis BCG intradermal vaccination and shuttle live bacilli to the draining lymph nodes [J].
Abadie, V ;
Badell, E ;
Douillard, P ;
Ensergueix, D ;
Leenen, PJM ;
Tanguy, M ;
Fiette, L ;
Saeland, S ;
Gicquel, B ;
Winter, N .
BLOOD, 2005, 106 (05) :1843-1850
[2]
THE INTEGRIN VLA-4 SUPPORTS TETHERING AND ROLLING IN FLOW ON VCAM-1 [J].
ALON, R ;
KASSNER, PD ;
CARR, MW ;
FINGER, EB ;
HEMLER, ME ;
SPRINGER, TA .
JOURNAL OF CELL BIOLOGY, 1995, 128 (06) :1243-1253
[3]
JAM-2, a novel immunoglobulin superfamily molecule, expressed by endothelial and lymphatic cells [J].
Aurrand-Lions, M ;
Duncan, L ;
Ballestrem, C ;
Imhof, BA .
JOURNAL OF BIOLOGICAL CHEMISTRY, 2001, 276 (04) :2733-2741
[4]
MIGRATION PATTERNS OF DENDRITIC LEUKOCYTES [J].
AUSTYN, JM .
RESEARCH IN IMMUNOLOGY, 1989, 140 (09) :898-902
[5]
Functionally specialized junctions between endothelial cells of lymphatic vessels [J].
Baluk, Peter ;
Fuxe, Jonas ;
Hashizume, Hiroya ;
Romano, Talia ;
Lashnits, Erin ;
Butz, Stefan ;
Vestweber, Dietmar ;
Corada, Monica ;
Molendini, Cinzia ;
Dejana, Elisabetta ;
McDonald, Donald M. .
JOURNAL OF EXPERIMENTAL MEDICINE, 2007, 204 (10) :2349-2362
[6]
LYVE-1, a new homologue of the CD44 glycoprotein, is a lymph-specific receptor for hyaluronan [J].
Banerji, S ;
Ni, J ;
Wang, SX ;
Clasper, S ;
Su, J ;
Tammi, R ;
Jones, M ;
Jackson, DG .
JOURNAL OF CELL BIOLOGY, 1999, 144 (04) :789-801
[7]
Dynamic interaction of VCAM-1 and ICAM-1 with moesin and ezrin in a novel endothelial docking structure for adherent leukocytes [J].
Barreiro, O ;
Yáñez-Mó, M ;
Serrador, JM ;
Montoya, MC ;
Vicente-Manzanares, M ;
Tejedor, R ;
Furthmayr, H ;
Sánchez-Madrid, F .
JOURNAL OF CELL BIOLOGY, 2002, 157 (07) :1233-1245
[8]
ENDOTHELIAL LEUKOCYTE ADHESION MOLECULE-1 - AN INDUCIBLE RECEPTOR FOR NEUTROPHILS RELATED TO COMPLEMENT REGULATORY PROTEINS AND LECTINS [J].
BEVILACQUA, MP ;
STENGELIN, S ;
GIMBRONE, MA ;
SEED, B .
SCIENCE, 1989, 243 (4895) :1160-1165
[9]
BOGEN SA, 1992, AM J PATHOL, V141, P843
[10]
JAM-C regulates unidirectional monocyte transendothelial migration in inflammation [J].
Bradfield, Paul F. ;
Scheiermann, Christoph ;
Nourshargh, Sussan ;
Ody, Christiane ;
Luscinskas, Francis W. ;
Rainger, G. Ed ;
Nash, Gerard B. ;
Miljkovic-Licina, Marijana ;
Aurrand-Lions, Michel ;
Imhof, Beat A. .
BLOOD, 2007, 110 (07) :2545-2555