Respiratory disease caused by a species B2 Adenovirus in a military camp in Turkey

被引:78
作者
Chmielewicz, B
Benzler, J
Pauli, G
Krause, G
Bergmann, F
Schweiger, B
机构
[1] Robert Koch Inst, Projektgrp 11, D-13353 Berlin, Germany
[2] Robert Koch Inst, FG Surveillance 32, D-1000 Berlin, Germany
[3] Robert Koch Inst, Zentrum Biol Sicherheit, D-1000 Berlin, Germany
[4] Robert Koch Inst, FG Virale Infekt 12, D-1000 Berlin, Germany
[5] Univ Med, Charite, Dept Infect Dis, Berlin, Germany
关键词
adenoviridae; acute respiratory disease; phylogeny; genotype; 11a;
D O I
10.1002/jmv.20441
中图分类号
Q93 [微生物学];
学科分类号
071005 ; 100705 ;
摘要
In April 2004, two patients were admitted to hospital in Berlin, Germany, with clinical signs of acute respiratory infection after returning from a military exercise in their home country of Turkey. They were admitted to a high security infectious disease unit as epidemiological data pointed to an outbreak of unknown etiology. Samples taken at the time of admission proved to be strongly positive for Adenovirus by PCR, but negative for Influenza A/H1N1 virus, Influenza A/H3N2 virus, Influenza B virus, Respiratory syncytial virus, and SARS coronavirus. No evidence for bacterial infection was obtained by serological tests and blood cultures. The adenovirus detected was characterized further by genotyping and was identified as a species B2 virus with the highest similarity to adenovirus type 11a.
引用
收藏
页码:232 / 237
页数:6
相关论文
共 33 条
[1]   Rapid typing of human adenoviruses by a general PCR combined with restriction endonuclease analysis [J].
Allard, A ;
Albinsson, B ;
Wadell, G .
JOURNAL OF CLINICAL MICROBIOLOGY, 2001, 39 (02) :498-505
[2]   Reemergence of adenovirus type 4 acute respiratory disease in military trainees: Report of an outbreak during a lapse in vaccination [J].
Barraza, EM ;
Ludwig, SL ;
Gaydos, JC ;
Brundage, JF .
JOURNAL OF INFECTIOUS DISEASES, 1999, 179 (06) :1531-1533
[3]   Subgroup B adenovirus type 35 early region 3 mRNAs differ from those of the subgroup C adenoviruses [J].
Basler, CF ;
Horwitz, MS .
VIROLOGY, 1996, 215 (02) :165-177
[4]   Molecular analysis of adenovirus isolates from vaccinated and unvaccinated young adults [J].
Blasiole, DA ;
Metzgar, D ;
Daum, LT ;
Ryan, MAK ;
Wu, JG ;
Wills, C ;
Le, CT ;
Freed, NE ;
Hansen, CJ ;
Gray, GC ;
Russell, KL .
JOURNAL OF CLINICAL MICROBIOLOGY, 2004, 42 (04) :1686-1693
[5]  
CHMIELEWICZ B, IN PRESS CLIN CHEM
[6]   Analysis of 15 adenovirus hexon proteins reveals the location and structure of seven hypervariable regions containing serotype-specific residues [J].
CrawfordMiksza, L ;
Schnurr, DP .
JOURNAL OF VIROLOGY, 1996, 70 (03) :1836-1844
[7]   Evaluation of a rapid quantitative diagnostic test for adenovirus type 4 [J].
Faix, DJ ;
Houng, HSH ;
Gaydos, JC ;
Liu, SKS ;
Connors, JT ;
Brown, X ;
Asher, LV ;
Vaughn, DW ;
Binn, LN .
CLINICAL INFECTIOUS DISEASES, 2004, 38 (03) :391-397
[8]  
Felsenstein J., 2005, PHYLIP PHYLOGENY INF, DOI DOI 10.1111/J.1096-0031.1989.TB00562.X
[9]  
FIELDS BN, 1996, VIROLOGY, P979
[10]   Adult adenovirus infections: Loss of orphaned vaccines precipitates military respiratory disease epidemics [J].
Gray, GC ;
Goswami, PR ;
Malasig, MD ;
Hawksworth, AW ;
Trump, DH ;
Ryan, MA ;
Schnurr, DP .
CLINICAL INFECTIOUS DISEASES, 2000, 31 (03) :663-670