IgA responses in the intestinal mucosa against pathogenic and non-pathogenic microorganisms

被引:228
作者
Macpherson, AJ [1 ]
Hunziker, L [1 ]
McCoy, K [1 ]
Lamarre, A [1 ]
机构
[1] Univ Spital Zurich, Inst Expt Immunol, CH-8091 Zurich, Switzerland
关键词
IgA; bacteria; viruses; intestinal mucosa;
D O I
10.1016/S1286-4579(01)01460-5
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
IgA is the most abundant immunoglobulin produced in mammals; most is secreted as a dimer across mucous membranes. This review discusses the different mechanisms of induction of IgA, and its role in protecting mucosal surfaces against pathogenic and non-pathogenic microorganisms. (C) 2001 Editions scientifiques et medicales Elsevier SAS.
引用
收藏
页码:1021 / 1035
页数:15
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